MIND AND KIDNEY REPORT OF THE LAUREAT OF THE BIG GOLD MEDAL NAMED AFTER M.V. LOMONOSOV RAS 2022

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

The report, presented at the General Meeting of the Members of the Russian Academy of Sciences on May 24, 2023, was devoted to the results of the author’s research on the physiology of the kidney and water-salt balance, and the practical significance of the results obtained. The author noted that the kidneys provide conditions for the stability of the volume of each cell of the body, maintaining the constancy of blood osmolality, blood volume in the vessels and the total volume of extracellular fluid in the body, constancy of blood pressure, the desired level of blood clotting; the kidneys are involved in regulating the balance of inorganic ions, digesting proteins, hydrolyzing altered proteins in the blood serum, in the synthesis of glucose in its deficiency, maintaining a constant concentration of many organic substances in the blood serum, hormone secretion, and many other processes.

Yu.V. Natochin defends the point of view, according to which the kidney is both an organ for excreting unnecessary substances from the blood and storing the necessary substances in it; it is the kidney that allows you to create an ideal composition of the environment surrounding every cell of the body. Another important postulate concerns the origin of life on Earth. The author disputes the widespread hypothesis about the origin of life in the sea water environment, since, in order to ensure the synthesis of polypeptides, the concentration of inorganic substances, in particular potassium ions, must be equal inside and outside the cell in the first emerging cell.

About the authors

Yu. V. Natochin

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of Sciences

Author for correspondence.
Email: natochin1@mail.ru
Russia, St. Petersburg

References

  1. Kriz W., Bankir L., Bulger R.E. et al. A standard nomenclature for structures of the kidney // Amer. J. Physiology, Renal, Fluid and Electrolyte Physiology. 1988. V. 254. № 23. P. F1–F8.
  2. Smith H.W. The Kidney: Structure and Function in Health and Disease. New York.: Oxford Univ. Press, 1951.
  3. Hediger M.A., Mouht D.B., Rolfs A., Romero M.F. The molecular basis of solute transport // Brenner B.M., Brenner and Rector’s the Kidney. Philadelphia.: Saunders, 2004. P. 260–308.
  4. Brenner B. (Ed.) The Kidney. 8 ed. Philadelphia: Saunders, Elsevier, 2008.
  5. Наточин Ю.В. Ионорегулирующая функция почек. Л.: Наука, 1976.
  6. Natocnin Yu.V. Evolutionary aspects of renal function // Kidney International. 1996. № 49. P. 1539–1542.
  7. Natochin Yu.V., Chernigovskaya T.V. Evolutionary Physiology: History, Principles // Comp. Biochem. Physiol. 1997. V. 118A. № 1. P. 63–79.
  8. Баркрофт Дж. Основные черты архитектуры физиологических функций. М.−Л.: Биомедгиз, 1937.
  9. Seliverstova E.V., Burmakin M.V., Natochin Yu.V. Renal clearance of absorbed intact GFP in the frog and rat intestine // Comp. Physiol. Biochem. 2007. A147. P. 1067–1073.
  10. Наточин Ю.В. Физиологическая эволюция животных: натрий – ключ к разрешению противоречий // Вестник РАН. 2007. № 11. С. 999–1010.
  11. Dubina M.V., Vyazmin S.Y., Boitsov V.M. et al. Potassium ions are more effective than sodium in salt induced peptide formation // Orig. Life Evol. Biosph. 2013. № 43. P. 109–117.
  12. Наточин Ю.В., Кутина А.В., Марина А.С., Шахматова Е.И. Стимул секреции глюкагоноподобного пептида-1 у крыс // Доклады Академии наук. 2018. № 5. С. 593–596.
  13. Наточин Ю.В., Марина А.С., Шахматова Е.И. Каскадная система регуляции осмотического гомеостаза // Доклады РАН. Науки о жизни. 2020. № 1. С. 77–80.
  14. Natochin Yu.V., Golosova D.V. Vasopressin receptor subtypes and renal sodium transport // Vitamins and Hormones. 2020. V. 113. P. 239–258.
  15. Наточин Ю.В., Соколова М.М., Васильева В.Ф., Балаховский И.С. Исследование функции почек у экипажа космического корабля “Восход” // Космич. исследования. 1965. № 6. С. 935–939.
  16. Leach Huntoon C.S., Grigoriev A.I., Natochin Yu.V. Fluid and Electrolyte Regulation in Spacefligth. San Diego: American Astronautical Society Publication, 1998.
  17. Наточин Ю.В., Прокопенко А.В., Кузнецова А.А., Шахматова Е.И. Функциональная диагностика синдрома неадекватной секреции антидиуретического гормона при пневмонии у детей // Педиатрия. 2020. № 2. С. 95–101.
  18. Natochin Yu.V., Lukianenko V.I., Kirsanov V.I. et al. Features of osmotic and ionic regulations (Acipenser güldenstädti Brand) // Comp. Biochem. Physiol. 1985. V. 80A. № 3. P. 297–302.
  19. Наточин Ю.В., Чернышев О.Б. Концентрация электролитов в сыворотке крови как предвестник тяжёлого течения COVID-19 // Нефрология. 2022. № 1. С. 27–33.

Supplementary files

Supplementary Files
Action
1. JATS XML
2.

Download (192KB)
3.

Download (596KB)
4.

Download (299KB)
5.

Download (1MB)
6.

Download (167KB)
7.

Download (1MB)
8.

Download (181KB)
9.

Download (1MB)
10.

Download (108KB)

Copyright (c) 2023 Ю.В. Наточин

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies