电邮这篇文章 Conservative Protein RCC1 Is a New Component of Black Bands of Drosophila melanogaster Polytene Chromosomes
- 作者: Zykova T.Y.1, Maltseva M.V.1, Demakov S.A.1, Pokholkova G.V.1, Veryaskina Y.A.1, Lavrik O.I.2, Kolesnikova T.D.1, Zhimulev I.F.1
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隶属关系:
- Institute of Molecular and Cellular Biology
- Institute of Chemical Biology and Fundamental Medicine
- 期: 卷 54, 编号 2 (2023)
- 页面: 176-180
- 栏目: Short communications
- URL: https://journals.rcsi.science/0475-1450/article/view/137055
- DOI: https://doi.org/10.31857/S0475145023020076
- EDN: https://elibrary.ru/XFQNTP
- ID: 137055
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详细
Previously, the RCC1 gene (Regulator of Chromosome Сondensation 1) was characterized, which is considered a regulator of chromosome condensation in the cell cycle. This gene encodes a nuclear protein whose amino acid sequence is highly conserved among all eukaryotes and consists of seven repeating units. We have shown that all the most prominent black bands of polytene chromosomes (about 250) and the chromocenter bind antibodies to this protein. We found that antibodies to the xenopus RCC1 protein specifically bind to the Drosophila and human RCC1 protein, while in Drosophila lines with under replication suppression, the relative amount of the RCC1 protein increases compared to the wild type.
作者简介
T. Zykova
Institute of Molecular and Cellular Biology
编辑信件的主要联系方式.
Email: vatolina@mcb.nsc.ru
Russia, 630090, Novosibirsk, prosp. ak. Lavrentieva 8/2
M. Maltseva
Institute of Molecular and Cellular Biology
Email: vatolina@mcb.nsc.ru
Russia, 630090, Novosibirsk, prosp. ak. Lavrentieva 8/2
S. Demakov
Institute of Molecular and Cellular Biology
Email: vatolina@mcb.nsc.ru
Russia, 630090, Novosibirsk, prosp. ak. Lavrentieva 8/2
G. Pokholkova
Institute of Molecular and Cellular Biology
Email: vatolina@mcb.nsc.ru
Russia, 630090, Novosibirsk, prosp. ak. Lavrentieva 8/2
Yu. Veryaskina
Institute of Molecular and Cellular Biology
Email: vatolina@mcb.nsc.ru
Russia, 630090, Novosibirsk, prosp. ak. Lavrentieva 8/2
O. Lavrik
Institute of Chemical Biology and Fundamental Medicine
Email: vatolina@mcb.nsc.ru
Russia, 630090, Novosibirsk, prosp. ak. Lavrentieva 8
T. Kolesnikova
Institute of Molecular and Cellular Biology
Email: vatolina@mcb.nsc.ru
Russia, 630090, Novosibirsk, prosp. ak. Lavrentieva 8/2
I. Zhimulev
Institute of Molecular and Cellular Biology
Email: vatolina@mcb.nsc.ru
Russia, 630090, Novosibirsk, prosp. ak. Lavrentieva 8/2
参考
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