Phytohormones affect the differentiation of human dermal fibroblasts via UPR activation
- Autores: Turishcheva E.1, Vildanova M.1, Vishnyakova P.2,3, Matveeva D.4, Saidova A.1, Onishchenko G.1, Smirnova E.1
-
Afiliações:
- Faculty of Biology, Lomonosov Moscow State University
- National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of Ministry of Healthcare of Russian Federation
- Peoples’ Friendship University of Russia
- Institute of Biomedical Problems, Russian Academy of Sciences
- Edição: Volume 88, Nº 6 (2023)
- Páginas: 995-1010
- Seção: Articles
- URL: https://journals.rcsi.science/0320-9725/article/view/144303
- DOI: https://doi.org/10.31857/S032097252306009X
- EDN: https://elibrary.ru/EFPTLN
- ID: 144303
Citar
Resumo
Palavras-chave
Sobre autores
E. Turishcheva
Faculty of Biology, Lomonosov Moscow State University
Email: kitten-caterina@yandex.ru
119991 Moscow, Russia
M. Vildanova
Faculty of Biology, Lomonosov Moscow State University119991 Moscow, Russia
P. Vishnyakova
National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of Ministry of Healthcare of Russian Federation;Peoples’ Friendship University of Russia117997 Moscow, Russia;117198 Moscow, Russia
D. Matveeva
Institute of Biomedical Problems, Russian Academy of Sciences123007 Moscow, Russia
A. Saidova
Faculty of Biology, Lomonosov Moscow State University119991 Moscow, Russia
G. Onishchenko
Faculty of Biology, Lomonosov Moscow State University119991 Moscow, Russia
E. Smirnova
Faculty of Biology, Lomonosov Moscow State University119991 Moscow, Russia
Bibliografia
- Desai, V. D., Hsia, H. C., and Schwarzbauer, J. E. (2014) Reversible modulation of myofibroblast differentiation in adipose-derived mesenchymal stem cells, PLoS One, 9, e86865, doi: 10.1371/journal.pone.0086865.
- Heindryckx, F., Binet, F., Ponticos, M., Rombouts, K., Lau, J., et al. (2016) Endoplasmic reticulum stress enhances fibrosis through IRE 1α-mediated degradation of miR-150 and XBP-1 splicing, EMBO Mol. Med., 8, 729-744, doi: 10.15252/emmm.201505925.
- Hinz, B. (2016) The role of myofibroblasts in wound healing, Curr. Res. Transl. Med., 64, 171-177, doi: 10.1016/j.retram.2016.09.003.
- Ko, U. H., Choi, J., Choung, J., Moon, S., and Shin, J. H. (2019) Physicochemically tuned myofibroblasts for wound healing strategy, Sci. Rep., 9, 16070, doi: 10.1038/s41598-019-52523-9.
- Las Heras, K., Igartua, M., Santos-Vizcaino, E., and Hernandez, R. M. (2020) Chronic wounds: Current status, available strategies and emerging therapeutic solutions, J. Control. Release, 328, 532-550, doi: 10.1016/j.jconrel.2020.09.039.
- Zou, M. L., Teng, Y. Y., Wu, J. J., Liu, S. Y., Tang, X. Y., Jia, Y., Chen, Z. H., Zhang, K. W., Sun, Z. L., Li, X., Ye, J. X., Xu, R. S., and Yuan, F. L. (2021) Fibroblasts: heterogeneous cells with potential in regenerative therapy for scarless wound healing, Front. Cell Dev. Biol., 9, 713605, doi: 10.3389/fcell.2021.713605.
- Talchai, C., Xuan, S., Lin, H. V., Sussel, L., and Accili, D. (2012) Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure, Cell, 150, 1223-1234, doi: 10.1016/j.cell.2012.07.029.
- Efrat, S. (2019) Beta-cell dedifferentiation in type 2 diabetes: concise review, STEM Cells, 37, 1267-1272, doi: 10.1002/stem.3059.
- Lenghel, A., Gheorghita, A. M., Vacaru, A. M., and Vacaru, A.-M. (2021) What is the sweetest UPR flavor for the β-cell? That is the question, Front. Endocrinol., 11, 614123, doi: 10.3389/fendo.2020.614123.
- Eastell, R., O'Neill, T. W., Hofbauer, L. C., Langdahl, B., Reid, I. R., Gold, D. T., and Cummings, S. R. (2016) Postmenopausal osteoporosis, Nat. Rev. Dis. Primers, 2, 16069, doi: 10.1038/nrdp.2016.69.
- Zhang, W., Feng, D., Li, Y., Iida, K., McGrath, B., and Cavener, D. R. (2006) PERK EIF2AK3 control of pancreatic β cell differentiation and proliferation is required for postnatal glucose homeostasis, Cell Metab., 4, 491-497, doi: 10.1016/j.cmet.2006.11.002.
- Saito, A., Ochiai, K., Kondo, S., Tsumagari, K., Murakami, T., Cavener, D. R., and Imaizumi, K. (2011) Endoplasmic reticulum stress response mediated by the PERK-eIF2-ATF4 pathway is involved in osteoblast differentiation induced by BMP2, J. Biol. Chem., 286, 4809-4818, doi: 10.1074/jbc.M110.152900.
- Baek, H. A., Kim, D. S., Park, H. S., Jang, K. Y., Kang, M. J., Lee, D. G., Moon, W. S., Chae, H. J., and Chung, M. J. (2012) Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts, Am. J. Resp. Cell Mol., 46, 731-739, doi: 10.1165/rcmb.2011-0121OC.
- Jang, W.-G., Kim, E.-J., Kim, D.-K., Ryoo, H.-M., Lee, K.-B., Kim, S. H., Choi, H. S., and Koh, J. T. (2012) BMP2 protein regulates osteocalcin expression via Runx2-mediated Atf6 gene transcription, J. Biol. Chem., 287, 905-915, doi: 10.1074/jbc.M111.253187.
- Chan, J. Y., Luzuriaga, J., Bensellam, M., Biden, T. J., and Laybutt, D. R. (2013) Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes, Diabetes, 62, 1557-1568, doi: 10.2337/db12-0701.
- Matsuzaki, S., Hiratsuka, T., Taniguchi, M., Shingaki, K., Kubo, T., Kiya, K., Fujiwara, T., Kanazawa, S., Kanematsu, R., Maeda, T., Takamura, H., Yamada, K., Miyoshi, K., Hosokawa, K., Tohyama, M., and Katayama, T. (2015) Physiological ER stress mediates the differentiation of fibroblasts, PLoS One, 10, e0123578, doi: 10.1371/journal.pone.0123578.
- Chen, Y. C., Chen, B. C., Huang, H. M., Lin, S. H., and Lin, C. H. (2019) Activation of PERK in ET-1-and thrombin-induced pulmonary fibroblast differentiation: inhibitory effects of curcumin, J. Cell. Physiol., 234, 15977-15988, doi: 10.1002/jcp.28256.
- Turishcheva, E., Vildanova, M., Onishchenko, G., and Smirnova, E. (2022) The role of endoplasmic reticulum stress in differentiation of cells of mesenchymal origin, Biochemistry (Moscow), 87, 916-931, doi: 10.1134/S000629792209005X.
- Budovsky, A., Yarmolinsky, L., and Ben-Shabat, S. (2015) Effect of medicinal plants on wound healing, Wound Repair Regen., 23, 171-183, doi: 10.1111/wrr.12274.
- Alamgir, A. N. M. (2018) Therapeutic Use of Medicinal Plants and Their Extracts: Volume 2. Phytochemistry and Bioactive Compounds, Springer Cham, doi: 10.1007/978-3-319-92387-1.
- Addis, R., Cruciani, S., Santaniello, S., Bellu, E., Sarais, G., Ventura, C., Maioli, M., and Pintore, G. (2020) Fibroblast proliferation and migration in wound healing by phytochemicals: evidence for a novel synergic outcome, Int. J. Med. Sci., 17, 1030-1042, doi: 10.7150/ijms.43986.
- Sharma, A., Khanna, S., Kaur, G., and Singh, I. (2021) Medicinal plants and their components for wound healing applications, Futur. J. Pharm. Sci., 7, 53, doi: 10.1186/s43094-021-00202-w.
- Kasamatsu, A., Iyoda, M., Usukura, K., Sakamoto, Y., Ogawara, K., Shiiba, M., Tanzawa, H., and Uzawa, K. (2012) Gibberellic acid induces α-amylase expression in adipose-derived stem cells, Int. J. Mol. Med., 30, 243-247, doi: 10.3892/ijmm.2012.1007.
- Vildanova, M., Vishnyakova, P., Saidova, A., Konduktorova, V., Onishchenko, G., and Smirnova, E. (2021) Gibberellic acid initiates ER stress and activation of differentiation in cultured human immortalized keratinocytes HaCaT and epidermoid carcinoma cells A431, Pharmaceutics, 13, 1813, doi: 10.3390/pharmaceutics13111813.
- Bruzzone, S., Bodrato, N., Usai, C., Guida, L., Moreschi, I., Nano, R., Antonioli, B., Fruscione, F., Magnone, M., Scarfì, S., De Flora, A., and Zocchi, E. (2008) Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger, J. Biol. Chem., 283, 32188-32197, doi: 10.1074/jbc.M802603200.
- Bruzzone, S., Magnone, M., Mannino, E., Sociali, G., Sturla, L., Fresia, C., Booz, V., Emionite, L., De Flora, A., and Zocchi, E. (2015) Abscisic acid stimulates glucagon-like peptide-1 secretion from L-cells and its oral administration increases plasma glucagon-like peptide-1 levels in rats, PLoS One, 10, e0140588, doi: 10.1371/journal.pone.0140588.
- Bruzzone, S., Battaglia, F., Mannino, E., Parodi, A., Fruscione, F., Basile, G., Salis, A., Sturla, L., Negrini, S., Kalli, F., Stringara, S., Filaci, G., Zocchi, E., and Fenoglio, D. (2012) Abscisic acid ameliorates the systemic sclerosis fibroblast phenotype in vitro, Biochem. Biophys. Res. Commun., 422, 70-74, doi: 10.1016/j.bbrc.2012.04.107.
- Zhang, W., Chen, D.-Q., Qi, F., Wang, J., Xiao, W.-Y., and Zhu, W. Z. (2010) Inhibition of calcium-calmodulin-dependent kinase ii suppresses cardiac fibroblast proliferation and extracellular matrix secretion, J. Cardiovasc. Pharmacol., 55, 96-105, doi: 10.1097/FJC.0b013e3181c9548b.
- Матвеева Д. К., Андреева Е. Р., Буравкова Л. Б. (2019) Выбор оптимального протокола получения децеллюляризованного внеклеточного маткрикса мезенхимальных стромальных клеток из жировой ткани человека, Вестн. Моск. Унив., 74, 294-300.
- Basalova, N., Sagaradze, G., Arbatskiy, M., Evtushenko, E., Kulebyakin, K., Grigorieva, O., Akopyan, Z., Kalinina, N., and Efimenko, A. (2020) Secretome of mesenchymal stromal cells prevents myofibroblasts differentiation by transferring fibrosis-associated microRNAs within extracellular vesicles, Cells, 9, 1272, doi: 10.3390/cells9051272.
- Zhivodernikov, I. V., Ratushnyy, A. Yu., Matveeva, D. K., and Buravkova, L. B. (2020) Extracellular matrix proteins and transcription of matrix-associated genes in mesenchymal stromal cells during modeling of the effects of microgravity, Bull. Exp. Biol. Med., 170, 230-232, doi: 10.1007/s10517-020-05040-z.
- Grigorieva, O. A., Vigovskiy, M. A., Dyachkova, U. D., Basalova, N. A., Aleksandrushkina, N. A., Kulebyakina, M. A., Zaitsev, I. L., Popov, V. S., and Efimenko, A. Y. (2021) Mechanisms of endothelial-to-mesenchymal transition induction by extracellular matrix components in pulmonary fibrosis, Bull. Exp. Biol. Med., 171, 523-531, doi: 10.1007/s10517-021-05264-7.
- Yang, M. C., O'Connor, A. J., Kalionis, B., and Heath, D. E. (2022) Improvement of mesenchymal stromal cell proliferation and differentiation via decellularized extracellular matrix on substrates with a range of surface chemistries, Front. Med. Technol., 4, 834123, doi: 10.3389/fmedt.2022.834123.
- Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A., and Speleman, F. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes, Genome Biol., 3, RESEARCH0034, doi: 10.1186/gb-2002-3-7-research0034.
- Турищева E. П., Вильданова М. С., Поташникова Д. М., Смирнова Е. А. (2020) Различная реакция биосинтетической системы дермальных фибробластов и клеток фибросаркомы человека на действие растительных гормонов, Цитология, 62, 566-580, doi: 10.31857/S0041377120080088.
- Kendall, R. T., and Feghali-Bostwick, C. A. (2014) Fibroblasts in fibrosis: novel roles and mediators, Front. Pharmacol., 5, 123, doi: 10.3389/fphar.2014.00123.
- Bonnans, C., Chou, J., and Werb, Z. (2014) Remodelling the extracellular matrix in development and disease, Nat. Rev. Mol. Cell Biol., 15, 786-801, doi: 10.1038/nrm3904.
- Vega-Avila, E., and Pugsley, M. K. (2011) An overview of colorimetric assay methods used to assess survival or proliferation of mammalian cells, Proc. West. Pharmacol. Soc., 54, 10-14.
- Sicari, D., Delaunay-Moisan, A., Combettes, L., Chevet, E., and Igbaria, A. (2020) A guide to assessing endoplasmic reticulum homeostasis and stress in mammalian systems, FEBS J., 287, 27-42, doi: 10.1111/febs.15107.
- Hetz, C. (2012) The unfolded protein response: controlling cell fate decisions under ER stress and beyond, Nat. Rev. Mol. Cell Biol., 13, 89-102, doi: 10.1038/nrm3270.
- Albacete-Albacete, L., Sanchez-Alvarez, M., and Del Pozo, M. A. (2021) Extracellular vesicles: an emerging mechanism governing the secretion and biological roles of tenascin-C, Front. Immunol., 12, 671485, doi: 10.3389/fimmu.2021.671485.
- Chen, X., Ding, C., Liu, W., Liu, X., Zhao, Y., Zheng, Y., Dong, L., Khatoon, S., Hao, M., Peng, X., Zhang, Y., and Chen, H. (2021) Abscisic acid ameliorates oxidative stress, inflammation, and apoptosis in thioacetamide-induced hepatic fibrosis by regulating the NF-kB signaling pathway in mice, Eur. J. Pharmacol., 891, 173652, doi: 10.1016/j.ejphar.2020.173652.
- Song, M., Peng, H., Guo, W., Luo, M., Duan, W., Chen, P., and Zhou, Y. (2019) Cigarette smoke extract promotes human lung myofibroblast differentiation by the induction of endoplasmic reticulum stress, Respiration, 98, 347-356, doi: 10.1159/000502099.
- Huang, W., Gu, H., Zhan, Z., Wang, R., Song, L., Zhang, Y., Zhang, Y., Li, S., Li, J., Zang, Y., Li, Y., and Qian, B. (2021) The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro, Platelets, 33, 462-470, doi: 10.1080/09537104.2021.1944616.
- Kovuru, N., Raghuwanshi, S., Sharma, D. S., Dahariya, S., Pallepati, A., and Gutti, R. K. (2020) Endoplasmic reticulum stress induced apoptosis and caspase activation is mediated through mitochondria during megakaryocyte differentiation, Mitochondrion, 50, 115-120, doi: 10.1016/j.mito.2019.10.009.
- Tai, Y., Woods, E. L., Dally, J., Kong, D., Steadman, R., Moseley, R., and Midgley, A. C. (2021) Myofibroblasts: function, formation, and scope of molecular therapies for skin fibrosis, Biomolecules, 11, 1095, doi: 10.3390/biom11081095.