“Double Punch”: Hepatitis C in Patients with Genetic Defects of Iron Metabolism
- Авторлар: Danilenko N.1, Siniauskaya M.1, Lukashyk S.2, Karpov I.2, Davydenko O.1
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Мекемелер:
- Institute of Genetics and Cytology, National Academy of Sciences of Belarus
- Belarusian State Medical University
- Шығарылым: Том 53, № 5 (2019)
- Беттер: 407-417
- Бөлім: Article
- URL: https://journals.rcsi.science/0095-4527/article/view/174143
- DOI: https://doi.org/10.3103/S0095452719050062
- ID: 174143
Дәйексөз келтіру
Аннотация
The review is focused on the development of chronic viral hepatitis C in patients with a genetic defect in the hereditary hemochromatosis (HFE) gene that controls iron metabolism. The effect of HFE gene mutations on the patient’s susceptibility to viral attack, the development of pathological processes in the liver, including the most severe complications, such as liver cirrhosis and hepatocellular carcinoma in chronic viral hepatitis C, and responsiveness of patients carrying the mutations to the treatment of viral hepatitis C are discussed.
Негізгі сөздер
Авторлар туралы
N. Danilenko
Institute of Genetics and Cytology, National Academy of Sciences of Belarus
Хат алмасуға жауапты Автор.
Email: cytoplasmic@mail.ru
Белоруссия, Minsk, 220072
M. Siniauskaya
Institute of Genetics and Cytology, National Academy of Sciences of Belarus
Email: svetlanalukashik@mail.ru
Белоруссия, Minsk, 220072
S. Lukashyk
Belarusian State Medical University
Хат алмасуға жауапты Автор.
Email: svetlanalukashik@mail.ru
Белоруссия, Minsk, 220116
I. Karpov
Belarusian State Medical University
Email: svetlanalukashik@mail.ru
Белоруссия, Minsk, 220116
O. Davydenko
Institute of Genetics and Cytology, National Academy of Sciences of Belarus
Email: svetlanalukashik@mail.ru
Белоруссия, Minsk, 220072