Bioinformatic search for Ca2+- and calmodulin-dependent protein kinases potentially associated with the regulation of plant cytoskeleton
- Authors: Novozhylov D.O.1, Karpov P.A.1, Blume Y.B.1
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Affiliations:
- Institute of Food Biotechnology and Genomics
- Issue: Vol 51, No 4 (2017)
- Pages: 239-246
- Section: Article
- URL: https://journals.rcsi.science/0095-4527/article/view/173639
- DOI: https://doi.org/10.3103/S0095452717040053
- ID: 173639
Cite item
Abstract
The paper presents the results of a bioinformatic search for Ca2+- and calmodulin-dependent protein kinases from Arabidopsis thaliana, which may potentially participate in cytoskeleton regulation. Homologues were chosen based on their similarity with the calmodulin-dependent protein kinases from Homo sapiens and Mus musculus, which modulate the structure and dynamic behavior of the cytoskeleton. In total, the sequences for the catalytic domains of 41 animal protein kinases and their known 42 plant homologues have been aligned. The closest animal and plant homologues have been determined using the methods of phylogenetic clusterization. According to the bioinformatic research results, the following plant protein kinases were selected as the most probable regulators of the plant cytoskeleton: CPK7, CPK14, CPK32, CPK17, CPK34, CPK20, CPK27, CPK16, CPK18, CPK28, CPK7, CRK2, CRK4, and CRK6.
Keywords
About the authors
D. O. Novozhylov
Institute of Food Biotechnology and Genomics
Author for correspondence.
Email: novozhylovd@gmail.com
Ukraine, Kyiv
P. A. Karpov
Institute of Food Biotechnology and Genomics
Email: novozhylovd@gmail.com
Ukraine, Kyiv
Ya. B. Blume
Institute of Food Biotechnology and Genomics
Email: novozhylovd@gmail.com
Ukraine, Kyiv