Syntheses of Melanotan II and YSL Amide by Ajiphase® Methodology
- 作者: Sanguliya T.1, Antipova A.1, Shkavrov S.1, Épshtein N.1
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隶属关系:
- National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
- 期: 卷 53, 编号 5 (2019)
- 页面: 462-466
- 栏目: Drug Synthesis Methods and Manufacturing Technology
- URL: https://journals.rcsi.science/0091-150X/article/view/245812
- DOI: https://doi.org/10.1007/s11094-019-02020-0
- ID: 245812
如何引用文章
详细
The promising antitumor peptides Melanotan II and YSL amide were synthesized for the first time in gram quantities in overall yields of 72 and 50%, respectively, by Ajiphase® methodology. This method was shown to be promising for peptide manufacturing. The proposed methods are as convenient as polymer-phase syntheses with the reagent consumption and associated analytical simplicity of classical solution syntheses.
作者简介
T. Sanguliya
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Email: NBEpshtejn@mephi.ru
俄罗斯联邦, Moscow, 115409
A. Antipova
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Email: NBEpshtejn@mephi.ru
俄罗斯联邦, Moscow, 115409
S. Shkavrov
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Email: NBEpshtejn@mephi.ru
俄罗斯联邦, Moscow, 115409
N. Épshtein
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
编辑信件的主要联系方式.
Email: NBEpshtejn@mephi.ru
俄罗斯联邦, Moscow, 115409