Synthesis and Antimicrobial, Antiprotozoal, and Fungistatic Activity of [5-(Amino-, Acylamino-, and 2-Pyridylmethylamino)-1-Alkylbenzimidazol-2-yl]Diphenylmethanols
- 作者: Koshchienko Y.1, Drobin Y.2, Zubenko A.2, Timoshevskii D.1, Fetisov L.2, Bodryakov A.2
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隶属关系:
- Research Institute of Physical and Organic Chemistry, Southern Federal University
- North-Caucasian Regional Scientific Research Veterinary Institute
- 期: 卷 52, 编号 8 (2018)
- 页面: 711-715
- 栏目: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245424
- DOI: https://doi.org/10.1007/s11094-018-1886-2
- ID: 245424
如何引用文章
详细
5-(Amino- and 2-pyridylmethylamino)-1-alkylbenzimidazoles treated sequentially with butyllithium and benzophenone synthesized [5-(amino- and 2-pyridylmethylamino)-1-alkylbenzimidazol-2-yl]diphenylmethanols. (5-Amino-1-methylbenzimidazol-2-yl)diphenylmethanol was converted by acyl chlorides into (5-acylamino-1-methylbenzimidazol-2-yl)diphenylmethanols. The products were shown to possess bacteriostatic activity against Gram-positive and Gram-negative bacteria (Staphylococcus aureus, Escherichia coli), antiprotozoal activity against the ciliate Colpoda steinii, and fungicidal activity against Penicillium italicum.
作者简介
Yu. Koshchienko
Research Institute of Physical and Organic Chemistry, Southern Federal University
编辑信件的主要联系方式.
Email: yukoshch@ipoc.sfedu.ru
俄罗斯联邦, Rostov-on-Don, 344090
Yu. Drobin
North-Caucasian Regional Scientific Research Veterinary Institute
Email: yukoshch@ipoc.sfedu.ru
俄罗斯联邦, Novocherkassk, 346421
A. Zubenko
North-Caucasian Regional Scientific Research Veterinary Institute
Email: yukoshch@ipoc.sfedu.ru
俄罗斯联邦, Novocherkassk, 346421
D. Timoshevskii
Research Institute of Physical and Organic Chemistry, Southern Federal University
Email: yukoshch@ipoc.sfedu.ru
俄罗斯联邦, Rostov-on-Don, 344090
L. Fetisov
North-Caucasian Regional Scientific Research Veterinary Institute
Email: yukoshch@ipoc.sfedu.ru
俄罗斯联邦, Novocherkassk, 346421
A. Bodryakov
North-Caucasian Regional Scientific Research Veterinary Institute
Email: yukoshch@ipoc.sfedu.ru
俄罗斯联邦, Novocherkassk, 346421