电邮这篇文章 Bioequivalence of a Dosage form of the New Drug Mefebut
- 作者: Smirnova L.A.1,2, Suchkov E.A.1,2, Ryabukha A.F.1,2, Kuznetsov K.A.1,2, Velikopol’skaya M.V.1, Tyurenkov I.N.1, Bakulin D.A.1, Stepanova É.F.3, Shevchenko A.M.3
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隶属关系:
- Volgograd State Medical University
- Volgograd Medical Scientific Center
- Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
- 期: 卷 52, 编号 6 (2018)
- 页面: 495-496
- 栏目: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245274
- DOI: https://doi.org/10.1007/s11094-018-1846-x
- ID: 245274
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详细
The bioequivalence of mefebut drug substance and its tablet dosage form was investigated by studying the main pharmacokinetic parameters and calculating the relative bioavailability. The results showed that mefebut circulated for up to 4 h in rabbit blood after peroral administration. The relative bioavailability was 97.4%.
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作者简介
L. Smirnova
Volgograd State Medical University; Volgograd Medical Scientific Center
编辑信件的主要联系方式.
Email: post@volgmed.ru
俄罗斯联邦, 1 Pavshikh Bortsov Sq, Volgograd, 400131; 1 Pavshikh Bortsov Sq, Volgograd, 400131
E. Suchkov
Volgograd State Medical University; Volgograd Medical Scientific Center
Email: post@volgmed.ru
俄罗斯联邦, 1 Pavshikh Bortsov Sq, Volgograd, 400131; 1 Pavshikh Bortsov Sq, Volgograd, 400131
A. Ryabukha
Volgograd State Medical University; Volgograd Medical Scientific Center
Email: post@volgmed.ru
俄罗斯联邦, 1 Pavshikh Bortsov Sq, Volgograd, 400131; 1 Pavshikh Bortsov Sq, Volgograd, 400131
K. Kuznetsov
Volgograd State Medical University; Volgograd Medical Scientific Center
Email: post@volgmed.ru
俄罗斯联邦, 1 Pavshikh Bortsov Sq, Volgograd, 400131; 1 Pavshikh Bortsov Sq, Volgograd, 400131
M. Velikopol’skaya
Volgograd State Medical University
Email: post@volgmed.ru
俄罗斯联邦, 1 Pavshikh Bortsov Sq, Volgograd, 400131
I. Tyurenkov
Volgograd State Medical University
Email: post@volgmed.ru
俄罗斯联邦, 1 Pavshikh Bortsov Sq, Volgograd, 400131
D. Bakulin
Volgograd State Medical University
Email: post@volgmed.ru
俄罗斯联邦, 1 Pavshikh Bortsov Sq, Volgograd, 400131
É. Stepanova
Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
Email: post@volgmed.ru
俄罗斯联邦, 11 Prosp. Kalinina, Pyatigorsk, 357532
A. Shevchenko
Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
Email: post@volgmed.ru
俄罗斯联邦, 11 Prosp. Kalinina, Pyatigorsk, 357532
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