Seasonal Oscillations in Statistical Mean Measures of Blood Composition and Blood Cell Morphology in Healthy White Rats

A. S. Pushkin; E. D. Drugova; S. A. Kamshilin; N. V. Obraztsov; O. V. Polekhina; S. I. Dvoretskaya; A. I. Churyumova

doi:10.1007/s11094-017-1692-2

Seasonal Oscillations in Statistical Mean Measures of Blood Composition and Blood Cell Morphology in Healthy White Rats

作者: Pushkin A.¹, Drugova E.¹, Kamshilin S.¹, Obraztsov N.¹, Polekhina O.¹, Dvoretskaya S.¹, Churyumova A.¹
隶属关系:
1. State Science Research Institute of Organic Chemistry and Technology
期: 卷 51, 编号 9 (2017)
页面: 777-782
栏目: Article
URL: https://journals.rcsi.science/0091-150X/article/view/244799
DOI: https://doi.org/10.1007/s11094-017-1692-2
ID: 244799

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
统计

详细

The aim of the present work was to identify seasonal oscillations in the composition and morphology of the blood in intact rats. Morphometric measures of blood were determined in 36 clinically healthy adult male rats in different seasons (spring, summer, and autumn) using the Mekos programmable system. Seasonal oscillations within established reference ranges were found and these need to be considered when performing preclinical studies of medicines in relation to their efficacy and safety.