Synthesis and Analgesic Activity of 9-Aryl-12-Imino-10,11-Dioxatricyclo[5.3.2.01,6]Dodecane-7,8,8-Tricarbonitriles and 3-Aryl-1,1,2,2-Tetracyanocyclopropanes
- 作者: Mar’yasov M.1, Sheverdov V.1, Nasakin O.1, Makhmudov R.2
-
隶属关系:
- I. N. Ul’yanov Chuvash State University
- Perm State University
- 期: 卷 50, 编号 9 (2016)
- 页面: 580-582
- 栏目: Search for New Drugs
- URL: https://journals.rcsi.science/0091-150X/article/view/244441
- DOI: https://doi.org/10.1007/s11094-016-1494-y
- ID: 244441
如何引用文章
详细
9-Aryl-12-imino-10,11-dioxatricyclo[5.3.2.01,6]dodecane-7,8,8-tricarbonitriles were synthesized via the reaction of 1-(2-oxocyclohexyl)ethane-1,1,2,2-tetracarbonitrile with aromatic aldehydes. The corresponding 3-aryl-1,1,2,2-tetracyanocyclopropanes were prepared from bromomalononitrile and aromatic aldehydes. The structures of the synthesized compounds were elucidated using IR, PMR, 13C NMR, and mass spectra. The analgesic activity of the synthesized compounds was investigated.
作者简介
M. Mar’yasov
I. N. Ul’yanov Chuvash State University
编辑信件的主要联系方式.
Email: marsikprovisor@mail.ru
俄罗斯联邦, Cheboksary, Chuvash Republic, 428010
V. Sheverdov
I. N. Ul’yanov Chuvash State University
Email: marsikprovisor@mail.ru
俄罗斯联邦, Cheboksary, Chuvash Republic, 428010
O. Nasakin
I. N. Ul’yanov Chuvash State University
Email: marsikprovisor@mail.ru
俄罗斯联邦, Cheboksary, Chuvash Republic, 428010
R. Makhmudov
Perm State University
Email: marsikprovisor@mail.ru
俄罗斯联邦, Perm, 614990