Assessment of Total Polyphenol Compounds in the Complex Phytopreparations Angionorm and Prostanorm Using the Folin-Ciocalteu Method
- 作者: Struchkov P.1, Beloborodov V.1, Il’yasov I.1, Savvatee A.1, Kolkhir V.2, Voskoboinikova I.2
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隶属关系:
- I. M. Sechenov First Moscow State Medical University, Russian Ministry of Health
- All-Russian Science Research Institute of Medicinal and Aromatic Herbs (VILAR)
- 期: 卷 50, 编号 7 (2016)
- 页面: 486-490
- 栏目: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244421
- DOI: https://doi.org/10.1007/s11094-016-1474-2
- ID: 244421
如何引用文章
详细
Studies reported here evaluated the applicability of the Folin-Ciocalteu method for assessing total phenolic compounds in the complex phytopreparation Angionorm, which is based on dry extract of a mixture of medicinal herb substances (MHS), i.e., seeds (fruits) of the common horse chestnut, licorice roots, hawthorn fruits, and dog rose fruits at a ratio of 30:15:20:35, and preparation Prostanorm, consisting of a 50% aqueous-alcoholic extract of a mixture of four MHS, i.e., St. John’s wort herb, Canadian goldenrod herb, licorice root, Echinacea rhizomes and roots in equal proportions by weight, and a preparation consisting of a dry extract based on this mixture. The method was adapted to analysis of total polyphenol content in medicinal formulations using these preparations. The method was validated in terms of specificity, correctness, linearity, and similarity, and satisfied the suitability criteria. Total polyphenol contexts were assayed as gallic acid equivalents. A decolorization method using the cationic radical ABTS was used to determine the antiradical activity of Angionorm and Prostanorm in trolox equivalent antioxidant capacity (TEAC) units and in terms of the IC50 (the concentration inhibiting activity by 50%). A correlation was found between the total content of phenolic compounds and antiradical activity.
作者简介
P. Struchkov
I. M. Sechenov First Moscow State Medical University, Russian Ministry of Health
编辑信件的主要联系方式.
Email: peter455@yandex.ru
俄罗斯联邦, Building 2, 8 Trubetskaya Street, Moscow
V. Beloborodov
I. M. Sechenov First Moscow State Medical University, Russian Ministry of Health
Email: peter455@yandex.ru
俄罗斯联邦, Building 2, 8 Trubetskaya Street, Moscow
I. Il’yasov
I. M. Sechenov First Moscow State Medical University, Russian Ministry of Health
Email: peter455@yandex.ru
俄罗斯联邦, Building 2, 8 Trubetskaya Street, Moscow
A. Savvatee
I. M. Sechenov First Moscow State Medical University, Russian Ministry of Health
Email: peter455@yandex.ru
俄罗斯联邦, Building 2, 8 Trubetskaya Street, Moscow
V. Kolkhir
All-Russian Science Research Institute of Medicinal and Aromatic Herbs (VILAR)
Email: peter455@yandex.ru
俄罗斯联邦, Building 1, 7 Grin Street, Moscow
I. Voskoboinikova
All-Russian Science Research Institute of Medicinal and Aromatic Herbs (VILAR)
Email: peter455@yandex.ru
俄罗斯联邦, Building 1, 7 Grin Street, Moscow