Antidiabetic and Antilipidemic Effects of Some Polar and Nonpolar Extracts of Securigera Securidaca Flowers
- 作者: Ahmadi A.1, Khalili M.2, Margedari S.1, Nahri-Niknafs B.1
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隶属关系:
- Department of Medicinal Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University
- Neurophysiology Research Center, Shahed University
- 期: 卷 49, 编号 11 (2016)
- 页面: 753-759
- 栏目: Medicinal Plants
- URL: https://journals.rcsi.science/0091-150X/article/view/244286
- DOI: https://doi.org/10.1007/s11094-016-1365-6
- ID: 244286
如何引用文章
详细
Medicinal plants are widely used for pharmacological agents. These herbs are very rich sources of bioactive compounds. Securigera securidaca is reputed in folk medicine as antidiabetic and antilipidemic drug. In this research, the effect of solvent’s polarity in bioactive extract of this plant was evaluated by GC/MS analysis. Then, hypoglycemic and hypolipidemic activities of different extracts were studied in diabetic rats and compared to glibenclamide.The results showed that carbon tetrachloride extract of this plant has the best and significant activity for reducing of glucose and lipid levels compared to other extracts because of higher content of sterols and fatty acids.
作者简介
Abbas Ahmadi
Department of Medicinal Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University
编辑信件的主要联系方式.
Email: ahmadikiau@yahoo.com
伊朗伊斯兰共和国, Tehran
Mohsen Khalili
Neurophysiology Research Center, Shahed University
Email: ahmadikiau@yahoo.com
伊朗伊斯兰共和国, Tehran
Shideh Margedari
Department of Medicinal Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University
Email: ahmadikiau@yahoo.com
伊朗伊斯兰共和国, Tehran
Babak Nahri-Niknafs
Department of Medicinal Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University
Email: ahmadikiau@yahoo.com
伊朗伊斯兰共和国, Tehran