Enviar artigo por via de e-mail Synthesis and Analgesic and Antibacterial Activity of 5-aryl-4-aroyl-1-(4-acetylaminosulfonylphenyl)-3-hydroxy-3-pyrrolin-2-ones
- Autores: Gein V.1, Bobrovskaya O.1, Seliverstov G.1, Makhmudov R.2, Novikova V.1
-
Afiliações:
- Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
- Perm State National Research University
- Edição: Volume 51, Nº 3 (2017)
- Páginas: 187-190
- Seção: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244526
- DOI: https://doi.org/10.1007/s11094-017-1579-2
- ID: 244526
Citar
Acesso aberto
Acesso está concedido
Somente assinantes
Resumo
A three-component reaction of aroylpyruvic acid methyl ester with a mixture of an aromatic aldehyde and 4-aminobenzenesulfonylacetamide (sulfacetamide) was used to synthesize 5-aryl-4-aroyl-1-(4-acetylaminosulfonylphenyl)-3-hydroxy-3-pyrrolin-2-ones. The structures of these compounds were established by IR, NMR, and 1H spectroscopy, along with mass spectrometry. The analgesic and antibacterial activities of these compounds were studied.
Sobre autores
V. Gein
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: geinvl48@mail.ru
Rússia, 2 Polevaya Street, Perm, 614900
O. Bobrovskaya
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Rússia, 2 Polevaya Street, Perm, 614900
G. Seliverstov
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Rússia, 2 Polevaya Street, Perm, 614900
R. Makhmudov
Perm State National Research University
Email: geinvl48@mail.ru
Rússia, Perm
V. Novikova
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Rússia, 2 Polevaya Street, Perm, 614900
