Email this article Spectrophotometric Determination of Sodium Prodronate in Tablets for Osteoporosis Treatment
- Authors: Bulyga D.M.1, Popova O.P.1, Rudakovskaya E.B.1, Kuvaeva Z.I.1, Lopatik D.V.1
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Affiliations:
- Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
- Issue: Vol 53, No 9 (2019)
- Pages: 871-875
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/246040
- DOI: https://doi.org/10.1007/s11094-019-02092-y
- ID: 246040
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Abstract
A spectrophotometric method for determining sodium prodronate in tablets by measuring the absorption at 237 ± 2 nm of a Cu(II)—prodronate complex in acetate buffer was developed and validated. The method met applicable requirements of the SP RB for quantitative analysis methods for drugs and could be recommended for use by the State Drug Quality Control Inspection and technical control departments of chemical and pharmaceutical plants.
About the authors
D. M. Bulyga
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Author for correspondence.
Email: aminoacid@ifoch.bas-net.by
Belarus, Minsk, 220072
O. P. Popova
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Email: aminoacid@ifoch.bas-net.by
Belarus, Minsk, 220072
E. B. Rudakovskaya
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Email: aminoacid@ifoch.bas-net.by
Belarus, Minsk, 220072
Z. I. Kuvaeva
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Email: aminoacid@ifoch.bas-net.by
Belarus, Minsk, 220072
D. V. Lopatik
Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Email: aminoacid@ifoch.bas-net.by
Belarus, Minsk, 220072
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