Spectrophotometric Determination of Sodium Prodronate in Tablets for Osteoporosis Treatment

D. M. Bulyga; O. P. Popova; E. B. Rudakovskaya; Z. I. Kuvaeva; D. V. Lopatik

doi:10.1007/s11094-019-02092-y

Spectrophotometric Determination of Sodium Prodronate in Tablets for Osteoporosis Treatment

Autores: Bulyga D.¹, Popova O.¹, Rudakovskaya E.¹, Kuvaeva Z.¹, Lopatik D.¹
Afiliações:
1. Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus
Edição: Volume 53, Nº 9 (2019)
Páginas: 871-875
Seção: Article
URL: https://journals.rcsi.science/0091-150X/article/view/246040
DOI: https://doi.org/10.1007/s11094-019-02092-y
ID: 246040

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A spectrophotometric method for determining sodium prodronate in tablets by measuring the absorption at 237 ± 2 nm of a Cu(II)—prodronate complex in acetate buffer was developed and validated. The method met applicable requirements of the SP RB for quantitative analysis methods for drugs and could be recommended for use by the State Drug Quality Control Inspection and technical control departments of chemical and pharmaceutical plants.