Targeted Transport as a Promising Method of Drug Delivery to the Central Nervous System (Review)
- Authors: Skorobogatova A.I.1,2, Terent’eva O.A.1,2, Vainshtein V.A.2, Okovityi S.V.1,2, Flisyuk E.V.2, Narkevich I.A.2
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Affiliations:
- N. P. Bekhtereva Institute of the Human Brain, Russian Academy of Sciences
- St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF
- Issue: Vol 53, No 9 (2019)
- Pages: 845-851
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/246030
- DOI: https://doi.org/10.1007/s11094-019-02088-8
- ID: 246030
Cite item
Abstract
Targeted transport systems for drug delivery to the central nervous system (CNS) are reviewed. A modern classification of dosage forms according to generation and characteristic features is presented. The main targeted delivery systems for CNS drugs based on nanocarriers such as liposomes, polymer nanoparticles, polymer micelles, solid lipid nanoparticles, and nanoparticles of chitosan and human serum albumin are examined.
About the authors
A. I. Skorobogatova
N. P. Bekhtereva Institute of the Human Brain, Russian Academy of Sciences; St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF
Author for correspondence.
Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 9 Akad. Pavlova St., St. Petersburg, 197376; 14A Prof. Popova St., St. Petersburg, 197376
O. A. Terent’eva
N. P. Bekhtereva Institute of the Human Brain, Russian Academy of Sciences; St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF
Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 9 Akad. Pavlova St., St. Petersburg, 197376; 14A Prof. Popova St., St. Petersburg, 197376
V. A. Vainshtein
St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF
Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 14A Prof. Popova St., St. Petersburg, 197376
S. V. Okovityi
N. P. Bekhtereva Institute of the Human Brain, Russian Academy of Sciences; St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF
Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 9 Akad. Pavlova St., St. Petersburg, 197376; 14A Prof. Popova St., St. Petersburg, 197376
E. V. Flisyuk
St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF
Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 14A Prof. Popova St., St. Petersburg, 197376
I. A. Narkevich
St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF
Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 14A Prof. Popova St., St. Petersburg, 197376