Targeted Transport as a Promising Method of Drug Delivery to the Central Nervous System (Review)


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Abstract

Targeted transport systems for drug delivery to the central nervous system (CNS) are reviewed. A modern classification of dosage forms according to generation and characteristic features is presented. The main targeted delivery systems for CNS drugs based on nanocarriers such as liposomes, polymer nanoparticles, polymer micelles, solid lipid nanoparticles, and nanoparticles of chitosan and human serum albumin are examined.

About the authors

A. I. Skorobogatova

N. P. Bekhtereva Institute of the Human Brain, Russian Academy of Sciences; St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF

Author for correspondence.
Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 9 Akad. Pavlova St., St. Petersburg, 197376; 14A Prof. Popova St., St. Petersburg, 197376

O. A. Terent’eva

N. P. Bekhtereva Institute of the Human Brain, Russian Academy of Sciences; St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF

Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 9 Akad. Pavlova St., St. Petersburg, 197376; 14A Prof. Popova St., St. Petersburg, 197376

V. A. Vainshtein

St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF

Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 14A Prof. Popova St., St. Petersburg, 197376

S. V. Okovityi

N. P. Bekhtereva Institute of the Human Brain, Russian Academy of Sciences; St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF

Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 9 Akad. Pavlova St., St. Petersburg, 197376; 14A Prof. Popova St., St. Petersburg, 197376

E. V. Flisyuk

St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF

Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 14A Prof. Popova St., St. Petersburg, 197376

I. A. Narkevich

St. Petersburg State Chemical Pharmaceutical Academy, Ministry of Health of the RF

Email: Anastasiya.Skorobogatova@pharminnotech.come
Russian Federation, 14A Prof. Popova St., St. Petersburg, 197376


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