Dinitrodibenzo [B,D]Oxepin-7(6h)-One Antiproliferative Activity Against Hepg2 Cells
- Authors: Li Q.1, Sun S.1, Gong X.1
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Affiliations:
- Heilongjiang University, School of Chemistry and Materials Science
- Issue: Vol 53, No 7 (2019)
- Pages: 624-627
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245906
- DOI: https://doi.org/10.1007/s11094-019-02050-8
- ID: 245906
Cite item
Abstract
The cytotoxic activity of twenty three new biphenyl compounds was investigated, and the IC50 value of 1,2-dinitrodibenzo [b,d]oxepin-7(6H)-one (DNDBO) was found to be the lowest among these compounds. The underlying mechanism of DNDBO-induced cell death was explored.
Keywords
About the authors
Qiang Li
Heilongjiang University, School of Chemistry and Materials Science
Email: gong_xianfeng@hotmail.com
China, Harbin, 150080
ShaoPing Sun
Heilongjiang University, School of Chemistry and Materials Science
Email: gong_xianfeng@hotmail.com
China, Harbin, 150080
XianFeng Gong
Heilongjiang University, School of Chemistry and Materials Science
Author for correspondence.
Email: gong_xianfeng@hotmail.com
China, Harbin, 150080