Two New Antioxidative Geniposides (Ulmoside C, Ulmoside D) and 10-O-Acetylgeniposidic Acid from Eucommia Ulmoides
- Authors: Xi Z.1, Khan S.1,2, Jichuan Z.1, Ullah H.3, Khan H.4, Zhang L.1
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Affiliations:
- State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology
- Institute of Chemical Sciences, Gomal University
- Department of Chemistry, Faculty of Arts and Basic Sciences, BUITEMS
- Department of Chemistry, University of Science and Technology
- Issue: Vol 52, No 4 (2018)
- Pages: 334-338
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245165
- DOI: https://doi.org/10.1007/s11094-018-1817-2
- ID: 245165
Cite item
Abstract
Eucommia ulmoides leaves were phytochemically and biologically studied for their antioxidant properties. Two new geniposides (ulmoside C and ulmoside D) and one known compound (10-O-acetylgeniposidic acid) were isolated from E. ulmoides. Evaluation of their free-radical scavenging activity with respect to DPPH, ABTS, and superoxide anions showed that ulmosides C and D possess outstanding properties with IC50 values of 6.5 ± 0.20 and 7.5 ± 0.01 μM (DPPH), 2.1 ± 0.007 and 3.5 ± 0.31 μM (ABTS), and 8.1 μ0.17 and 10 ± 0.09 μM (superoxide anion), respectively.
Keywords
About the authors
Zhang Xi
State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology
Email: zhanglq@mail.buct.edu.cn
China, Beijing
Shafiullah Khan
State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology; Institute of Chemical Sciences, Gomal University
Email: zhanglq@mail.buct.edu.cn
China, Beijing; D. I. Khan
Zhang Jichuan
State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology
Email: zhanglq@mail.buct.edu.cn
China, Beijing
Hamid Ullah
Department of Chemistry, Faculty of Arts and Basic Sciences, BUITEMS
Email: zhanglq@mail.buct.edu.cn
Pakistan, Takatu Campus (Main Campus), Quetta, 87300
Hidayatullah Khan
Department of Chemistry, University of Science and Technology
Email: zhanglq@mail.buct.edu.cn
Pakistan, Bannu, KP
Liqun Zhang
State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology
Author for correspondence.
Email: zhanglq@mail.buct.edu.cn
China, Beijing