Two New Antioxidative Geniposides (Ulmoside C, Ulmoside D) and 10-O-Acetylgeniposidic Acid from Eucommia Ulmoides


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Abstract

Eucommia ulmoides leaves were phytochemically and biologically studied for their antioxidant properties. Two new geniposides (ulmoside C and ulmoside D) and one known compound (10-O-acetylgeniposidic acid) were isolated from E. ulmoides. Evaluation of their free-radical scavenging activity with respect to DPPH, ABTS, and superoxide anions showed that ulmosides C and D possess outstanding properties with IC50 values of 6.5 ± 0.20 and 7.5 ± 0.01 μM (DPPH), 2.1 ± 0.007 and 3.5 ± 0.31 μM (ABTS), and 8.1 μ0.17 and 10 ± 0.09 μM (superoxide anion), respectively.

About the authors

Zhang Xi

State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology

Email: zhanglq@mail.buct.edu.cn
China, Beijing

Shafiullah Khan

State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology; Institute of Chemical Sciences, Gomal University

Email: zhanglq@mail.buct.edu.cn
China, Beijing; D. I. Khan

Zhang Jichuan

State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology

Email: zhanglq@mail.buct.edu.cn
China, Beijing

Hamid Ullah

Department of Chemistry, Faculty of Arts and Basic Sciences, BUITEMS

Email: zhanglq@mail.buct.edu.cn
Pakistan, Takatu Campus (Main Campus), Quetta, 87300

Hidayatullah Khan

Department of Chemistry, University of Science and Technology

Email: zhanglq@mail.buct.edu.cn
Pakistan, Bannu, KP

Liqun Zhang

State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology

Author for correspondence.
Email: zhanglq@mail.buct.edu.cn
China, Beijing


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