Acetoxybenzoylglycylglycines as Potential Cerebroprotective Compounds
- Authors: Brel’ A.K.1, Tyurenkov I.N.1, Lisina S.V.1, Popov S.S.1, Verkholyak D.V.1, Budaeva Y.N.1, Volotova E.V.1, Atapina N.V.1, Kurkin D.V.1
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Affiliations:
- Volgograd State Medical University, Ministry of Health of the Russian Federation
- Issue: Vol 52, No 1 (2018)
- Pages: 37-41
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244980
- DOI: https://doi.org/10.1007/s11094-018-1762-0
- ID: 244980
Cite item
Abstract
3,4,5-Trimethoxy- and 2-, 3-, and 4-acetoxybenzoylglycylglycines and their water-soluble potassium and lithium salts were synthesized. The cerebroprotective properties of the water-soluble potassium and lithium salts of acetoxybenzoylglycylglycines were studied experimentally. The most marked cerebroprotective proteins in cerebral ischemia were found with the lithium salt of 2-acetoxybenzoylglycylglycine.
About the authors
A. K. Brel’
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131
I. N. Tyurenkov
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131
S. V. Lisina
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131
S. S. Popov
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131
D. V. Verkholyak
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131
Yu. N. Budaeva
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131
E. V. Volotova
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131
N. V. Atapina
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131
D. V. Kurkin
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, 1 Pavshikh Bortsov Square, Volgograd, 400131