M-Dinitroaromatic Moiety as a Fragment of Biologically Active Compounds
- Authors: Piskov V.B.1, Chernyshev V.P.1, Karakotov S.D.1
-
Affiliations:
- Shchelkovo-Agrokhim Company
- Issue: Vol 49, No 11 (2016)
- Pages: 724-734
- Section: Search for New Drugs
- URL: https://journals.rcsi.science/0091-150X/article/view/244282
- DOI: https://doi.org/10.1007/s11094-016-1361-x
- ID: 244282
Cite item
Abstract
Data on the biological activities of compounds containing m-dinitroaromatic (m-DAr) moieties were presented and led to the conclusion that including this moiety in the structures of new biologically active compounds was promising. It was established that one nitro group in m-DAr could be replaced by trifluoromethyl without losing the biological activity of the obtained analogs.
About the authors
V. B. Piskov
Shchelkovo-Agrokhim Company
Email: chem@folium.ru
Russian Federation, 2 Zavodskaya St., Shchelkovo, Moscow, Oblast, 141101
V. P. Chernyshev
Shchelkovo-Agrokhim Company
Email: chem@folium.ru
Russian Federation, 2 Zavodskaya St., Shchelkovo, Moscow, Oblast, 141101
S. D. Karakotov
Shchelkovo-Agrokhim Company
Email: chem@folium.ru
Russian Federation, 2 Zavodskaya St., Shchelkovo, Moscow, Oblast, 141101