Мақаланы E-mail арқылы жіберу Search for Monoamine Oxidase Inhibitors among Pyrazoline and Pyrimidine Derivatives and Studying Luminescent Properties of the Obtained Compounds
- Авторлар: Isakhanyan A.1, Hakobyan N.1, Hovasyan Z.1, Grigoryan G.2, Mkhitaryan R.2, Yesayan D.2, Grigoryan A.1, Gasparyan H.1, Panosyan Н.1, Harutyunyan A.1
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Мекемелер:
- Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
- Yerevan State University
- Шығарылым: Том 94, № 1 (2024)
- Беттер: 80-91
- Бөлім: Articles
- URL: https://journals.rcsi.science/0044-460X/article/view/258228
- DOI: https://doi.org/10.31857/S0044460X24010065
- EDN: https://elibrary.ru/HLHZQA
- ID: 258228
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Аннотация
Cyclization of the (E)-3-aryl-1-(4-alkoxyphenyl)prop-2-en-1-ones with phenylhydrazine in an acidic medium leads to the 5-aryl-3-(4-alkoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazoles. Bubbling air through a solution of 5-(4-methoxyphenyl)-1-phenyl-3-(4-ethoxyphenyl)-4,5-dihydro-1H-pyrazole in ethylcellosolve resulted in an oxidation-dehydrogenation product, which characterized as the picrate of the corresponding pyrazole. The reaction of benzamidine and 4-methylbenzamidine hydrochlorides with substituted chalcones in а KOH–ethanol system leads to 2,4-diaryl-6-(4-alkoxyphenyl)pyrimidines. The luminescent and antimonoamine oxidase properties of the resulting systems were studied.
Толық мәтін
Авторлар туралы
A. Isakhanyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
Хат алмасуға жауапты Автор.
Email: anush.isakhanyan.51@mail.ru
ORCID iD: 0000-0002-1713-4908
Армения, Yerevan
N. Hakobyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
Email: anush.isakhanyan.51@mail.ru
ORCID iD: 0000-0002-3095-5938
Армения, Yerevan
Z. Hovasyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
Email: anush.isakhanyan.51@mail.ru
ORCID iD: 0000-0001-6698-7184
Армения, Yerevan
G. Grigoryan
Yerevan State University
Email: gevsgrig@ysu.am
ORCID iD: 0000-0002-0675-735X
Армения, Yerevan
R. Mkhitaryan
Yerevan State University
Email: gevsgrig@ysu.am
ORCID iD: 0009-0009-6277-2747
Армения, Yerevan
D. Yesayan
Yerevan State University
Email: gevsgrig@ysu.am
ORCID iD: 0009-0008-7243-6248
Ресей, Yerevan
A. Grigoryan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
Email: anush.isakhanyan.51@mail.ru
ORCID iD: 0000-0002-3834-3338
Ресей, Yerevan
H. Gasparyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
Email: anush.isakhanyan.51@mail.ru
ORCID iD: 0000-0002-8555-3733
Ресей, Yerevan
Н. Panosyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
Email: anush.isakhanyan.51@mail.ru
ORCID iD: 0000-0001-8311-6276
Ресей, Yerevan
A. Harutyunyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
Email: anush.isakhanyan.51@mail.ru
ORCID iD: 0000-0003-0641-5453
Ресей, Yerevan
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