Effect of medium acidity on the thermodynamics and kinetics of the reaction of pyridoxal 5′-phosphate with isoniazid in an aqueous solution
- 作者: Gamov G.1, Zavalishin M.1, Usacheva T.1, Sharnin V.1,2
-
隶属关系:
- Ivanovo State University of Chemistry and Technology
- Krestov Institute of Solution Chemistry
- 期: 卷 91, 编号 5 (2017)
- 页面: 843-849
- 栏目: Chemical Kinetics and Catalysis
- URL: https://journals.rcsi.science/0036-0244/article/view/169459
- DOI: https://doi.org/10.1134/S0036024417050107
- ID: 169459
如何引用文章
详细
Thermodynamic characteristics of the formation of the Schiff base between isoniazid and pyridoxal 5'-phosphate in an aqueous solution at different pH values of a medium are determined by means of spectrophotometry and calorimetric titration. The process kinetics is studied spectrophotometrically, and the reaction rate constants for the formation of the imine at different acidities of a medium are determined. Biochemical aspects of the binding of pyridoxal 5'-phosphate into stable compounds are discussed.
作者简介
G. Gamov
Ivanovo State University of Chemistry and Technology
编辑信件的主要联系方式.
Email: georgegamov38@gmail.com
俄罗斯联邦, Ivanovo, 153000
M. Zavalishin
Ivanovo State University of Chemistry and Technology
Email: georgegamov38@gmail.com
俄罗斯联邦, Ivanovo, 153000
T. Usacheva
Ivanovo State University of Chemistry and Technology
Email: georgegamov38@gmail.com
俄罗斯联邦, Ivanovo, 153000
V. Sharnin
Ivanovo State University of Chemistry and Technology; Krestov Institute of Solution Chemistry
Email: georgegamov38@gmail.com
俄罗斯联邦, Ivanovo, 153000; Ivanovo, 153045