Solution behavior of metoclopramide in aqueous-alcoholic solutions at 30°C
- Авторлар: Deosarkar S.1, Sawale R.1, Tawde P.1, Kalyankar T.2
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Мекемелер:
- School of Chemical Sciences
- School of Pharmacy
- Шығарылым: Том 90, № 7 (2016)
- Беттер: 1362-1366
- Бөлім: Physical Chemistry of Solutions
- URL: https://journals.rcsi.science/0036-0244/article/view/168440
- DOI: https://doi.org/10.1134/S0036024416070074
- ID: 168440
Дәйексөз келтіру
Аннотация
Densities (ρ) and refractive indices (nD) of solutions of antiemetic drug metoclopramide (4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide hydrochloride hydrate) in methanolwater and ethanol-water mixtures of different compositions were measured at 30°C. Apparent molar volume (φv) of the drug was calculated from density data and partial molar volumes (φv0) were determined from Massons relation. Concentration dependence of nD has been studied to determine refractive indices of solution at infinite dilution (nD0). Results have been interpreted in terms of solute-solvent interactions.
Негізгі сөздер
Авторлар туралы
S. Deosarkar
School of Chemical Sciences
Хат алмасуға жауапты Автор.
Email: sandeo24@yahoo.co.in
Үндістан, Nanded, 431606 (MS)
R. Sawale
School of Chemical Sciences
Email: sandeo24@yahoo.co.in
Үндістан, Nanded, 431606 (MS)
P. Tawde
School of Chemical Sciences
Email: sandeo24@yahoo.co.in
Үндістан, Nanded, 431606 (MS)
T. Kalyankar
School of Pharmacy
Email: sandeo24@yahoo.co.in
Үндістан, Nanded, 431606 (MS)