Responses of Blood System to Doxorubicin/Docetaxel Chemotherapy in Patients with Breast Cancer
- 作者: Goldberg V.1, Polyakova T.2,3, Popova N.1, Vysotskaya V.1, Simolina E.1, Dudnikova E.1, Goncharova N.1, Belevich Y.1, Grigor’ev E.1, Goldberg A.1, Dygai A.2
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隶属关系:
- Research Institute of Oncology
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
- Siberian State Medical University, Ministry of Health of Russian Federation
- 期: 卷 168, 编号 2 (2019)
- 页面: 275-279
- 栏目: Oncology
- URL: https://journals.rcsi.science/0007-4888/article/view/242403
- DOI: https://doi.org/10.1007/s10517-019-04690-y
- ID: 242403
如何引用文章
详细
We studied the effects of combined chemotherapy with doxorubicin/docetaxel on erythroid and granulocytic hematopoietic lineages with particular attention focused on their recovery in patients with stages III-IV breast cancer. Intensification of differentiation of erythroid and granulocytic CFU (even under conditions of their suppressed proliferation) provided the increase in the content of mature and morphologically differentiated elements in the bone marrow and peripheral blood. High proliferative activity of erythroid and granulomonocytic precursors resulted from enhanced production of hematopoiesis-stimulating activities by microenvironment elements.
作者简介
V. Goldberg
Research Institute of Oncology
编辑信件的主要联系方式.
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
T. Polyakova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical University, Ministry of Health of Russian Federation
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk; Tomsk
N. Popova
Research Institute of Oncology
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
V. Vysotskaya
Research Institute of Oncology
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
E. Simolina
Research Institute of Oncology
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
E. Dudnikova
Research Institute of Oncology
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
N. Goncharova
Research Institute of Oncology
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
Yu. Belevich
Research Institute of Oncology
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
E. Grigor’ev
Research Institute of Oncology
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
A. Goldberg
Research Institute of Oncology
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
A. Dygai
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: goldbergve@mail.ru
俄罗斯联邦, Tomsk
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