Role of Neurotrophic Factors BDNF and GDNF in Nervous System Adaptation to the Influence of Ischemic Factors
- 作者: Mitroshina E.1, Mishchenko T.1, Shishkina T.1, Vedunova M.1
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隶属关系:
- N. I. Lobachevsky Nizhny Novgorod National Research State University
- 期: 卷 167, 编号 4 (2019)
- 页面: 574-579
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241909
- DOI: https://doi.org/10.1007/s10517-019-04574-1
- ID: 241909
如何引用文章
详细
We developed a complex in vitro model of ischemic damage. Analysis of hippocampal cell viability in primary cultures after modeling of various stress factors revealed the features of action of the main pathological factors of ischemia. Neurotrophic factors BDNF and GDNF produced pronounced neuroprotective effect during modeling both the complex ischemic damage and its individual pathophysiological components. Neurotrophic factor GDNF produced the most pronounced protective effect.
作者简介
E. Mitroshina
N. I. Lobachevsky Nizhny Novgorod National Research State University
编辑信件的主要联系方式.
Email: helenmitroshina@gmail.com
俄罗斯联邦, Nizhny Novgorod
T. Mishchenko
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: helenmitroshina@gmail.com
俄罗斯联邦, Nizhny Novgorod
T. Shishkina
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: helenmitroshina@gmail.com
俄罗斯联邦, Nizhny Novgorod
M. Vedunova
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: helenmitroshina@gmail.com
俄罗斯联邦, Nizhny Novgorod
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