Отправить статью по E-mail Role of Neurotrophic Factors BDNF and GDNF in Nervous System Adaptation to the Influence of Ischemic Factors
- Авторы: Mitroshina E.1, Mishchenko T.1, Shishkina T.1, Vedunova M.1
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Учреждения:
- N. I. Lobachevsky Nizhny Novgorod National Research State University
- Выпуск: Том 167, № 4 (2019)
- Страницы: 574-579
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241909
- DOI: https://doi.org/10.1007/s10517-019-04574-1
- ID: 241909
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Аннотация
We developed a complex in vitro model of ischemic damage. Analysis of hippocampal cell viability in primary cultures after modeling of various stress factors revealed the features of action of the main pathological factors of ischemia. Neurotrophic factors BDNF and GDNF produced pronounced neuroprotective effect during modeling both the complex ischemic damage and its individual pathophysiological components. Neurotrophic factor GDNF produced the most pronounced protective effect.
Об авторах
E. Mitroshina
N. I. Lobachevsky Nizhny Novgorod National Research State University
Автор, ответственный за переписку.
Email: helenmitroshina@gmail.com
Россия, Nizhny Novgorod
T. Mishchenko
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: helenmitroshina@gmail.com
Россия, Nizhny Novgorod
T. Shishkina
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: helenmitroshina@gmail.com
Россия, Nizhny Novgorod
M. Vedunova
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: helenmitroshina@gmail.com
Россия, Nizhny Novgorod
