Comparative Analysis of Secretome of Human Umbilical Cord- and Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells
- 作者: Romanov Y.1,2, Volgina N.3, Vtorushina V.3, Romanov A.3, Dugina T.2, Kabaeva N.1, Sukhikh G.3
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隶属关系:
- National Medical Research Center for Cardiology, Ministry of Health of the Russian Federation
- Cord Blood Bank “CryoCenter”
- V. I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
- 期: 卷 166, 编号 4 (2019)
- 页面: 535-540
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241160
- DOI: https://doi.org/10.1007/s10517-019-04388-1
- ID: 241160
如何引用文章
详细
Production of cytokines and growth factors by cultured human umbilical cord tissue- and bone marrow-derived multipotent mesenchymal stromal cells was measured by multiplex analysis. In most cases, the concentrations of bioactive factors in the culture medium conditioned by umbilical cord-derived cells was ten- to hundred-times higher than in the medium conditioned by bone marrow-derived cells. These results suggest that both multipotent mesenchymal stromal cells from the umbilical cord and cell-free products can have more pronounced therapeutic effect in comparison with mesenchymal stromal cells obtained from “adult” sources.
作者简介
Yu. Romanov
National Medical Research Center for Cardiology, Ministry of Health of the Russian Federation; Cord Blood Bank “CryoCenter”
编辑信件的主要联系方式.
Email: romanov@cryocenter.ru
俄罗斯联邦, Moscow; Moscow
N. Volgina
V. I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: romanov@cryocenter.ru
俄罗斯联邦, Moscow
V. Vtorushina
V. I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: romanov@cryocenter.ru
俄罗斯联邦, Moscow
A. Romanov
V. I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: romanov@cryocenter.ru
俄罗斯联邦, Moscow
T. Dugina
Cord Blood Bank “CryoCenter”
Email: romanov@cryocenter.ru
俄罗斯联邦, Moscow
N. Kabaeva
National Medical Research Center for Cardiology, Ministry of Health of the Russian Federation
Email: romanov@cryocenter.ru
俄罗斯联邦, Moscow
G. Sukhikh
V. I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: romanov@cryocenter.ru
俄罗斯联邦, Moscow
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