Effect of Xylan Sulfates on Coagulation of Human Blood Plasma


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Sulfated derivatives of xylan (isolated from Bétula pubéscens wood) with average molecular weight ~34 kDa, sulfur content of 11.3-17.5%, a degree of substitution of 0.74-1.64 are anticoagulants of direct type of action. Antithrombin and antifactor Xa activities in three tested xylan samples did not differ and reached 30.8-31.8 and 13.5-14.3 U/mg, respectively.

作者简介

N. Drozd

National Research Center for Hematology, Ministry of Health of the Russian Federation

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Email: nndrozd@mail.ru
俄罗斯联邦, Moscow

S. Kuznetsova

Institute of Chemistry and Chemical Technology, Siberian Division of the Russian Academy of Science, Subdivision of the Krasnoyarsk Federal Research Center; Siberian Federal University

Email: nndrozd@mail.ru
俄罗斯联邦, Krasnoyarsk; Krasnoyarsk

V. Levdansky

Institute of Chemistry and Chemical Technology, Siberian Division of the Russian Academy of Science, Subdivision of the Krasnoyarsk Federal Research Center

Email: nndrozd@mail.ru
俄罗斯联邦, Krasnoyarsk

M. Mikhailenko

Institute of Chemistry of Solid Body and Mechanochemistry, Siberian Division of the Russian Academy of Science

Email: nndrozd@mail.ru
俄罗斯联邦, Novosibirsk


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