Email this article Effect of Xylan Sulfates on Coagulation of Human Blood Plasma
- Authors: Drozd N.N.1, Kuznetsova S.A.2,3, Levdansky V.A.2, Mikhailenko M.A.4
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Affiliations:
- National Research Center for Hematology, Ministry of Health of the Russian Federation
- Institute of Chemistry and Chemical Technology, Siberian Division of the Russian Academy of Science, Subdivision of the Krasnoyarsk Federal Research Center
- Siberian Federal University
- Institute of Chemistry of Solid Body and Mechanochemistry, Siberian Division of the Russian Academy of Science
- Issue: Vol 164, No 2 (2017)
- Pages: 158-161
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239437
- DOI: https://doi.org/10.1007/s10517-017-3947-z
- ID: 239437
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Abstract
Sulfated derivatives of xylan (isolated from Bétula pubéscens wood) with average molecular weight ~34 kDa, sulfur content of 11.3-17.5%, a degree of substitution of 0.74-1.64 are anticoagulants of direct type of action. Antithrombin and antifactor Xa activities in three tested xylan samples did not differ and reached 30.8-31.8 and 13.5-14.3 U/mg, respectively.
About the authors
N. N. Drozd
National Research Center for Hematology, Ministry of Health of the Russian Federation
Author for correspondence.
Email: nndrozd@mail.ru
Russian Federation, Moscow
S. A. Kuznetsova
Institute of Chemistry and Chemical Technology, Siberian Division of the Russian Academy of Science, Subdivision of the Krasnoyarsk Federal Research Center; Siberian Federal University
Email: nndrozd@mail.ru
Russian Federation, Krasnoyarsk; Krasnoyarsk
V. A. Levdansky
Institute of Chemistry and Chemical Technology, Siberian Division of the Russian Academy of Science, Subdivision of the Krasnoyarsk Federal Research Center
Email: nndrozd@mail.ru
Russian Federation, Krasnoyarsk
M. A. Mikhailenko
Institute of Chemistry of Solid Body and Mechanochemistry, Siberian Division of the Russian Academy of Science
Email: nndrozd@mail.ru
Russian Federation, Novosibirsk
