Effects of Multicide, Antibacterial Drug, on Staphylococcus Biomembranes
- 作者: Tetz G.1, Artemenko N.1, Yankovskii G.2, Kever L.3, Komissarchik Y.3, Tetz V.1
-
隶属关系:
- Department of Microbiology and Virology, I. P. Pavlov St. Petersburg First State Medical University, the Ministry of Health of the Russian Federation
- MISiS National Research Technological Institute
- Institute of Cytology, the Russian Academy of Sciences
- 期: 卷 163, 编号 6 (2017)
- 页面: 780-784
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239252
- DOI: https://doi.org/10.1007/s10517-017-3902-z
- ID: 239252
如何引用文章
详细
Drug penetration into bacterial biomembranes is one of the most important factors determining the efficiency of antibacterial therapy. Multicide, antibacterial drug, is a nanomolecule 1.3-2.0 nm in size, easily penetrating into staphylococcus biomembranes and causing rapid death of bacteria. The drug efficiency depends on its concentration and duration of exposure. Bacteria die as a result of cell wall perforation, which is associated with changes in its morphology and release of DNA from bacterial cell into the environment. Our results indicate the efficiency of primary damage to bacterial wall leading to elimination of biomembranes.
作者简介
G. Tetz
Department of Microbiology and Virology, I. P. Pavlov St. Petersburg First State Medical University, the Ministry of Health of the Russian Federation
Email: vtetzv@yahoo.com
俄罗斯联邦, St. Petersburg
N. Artemenko
Department of Microbiology and Virology, I. P. Pavlov St. Petersburg First State Medical University, the Ministry of Health of the Russian Federation
Email: vtetzv@yahoo.com
俄罗斯联邦, St. Petersburg
G. Yankovskii
MISiS National Research Technological Institute
Email: vtetzv@yahoo.com
俄罗斯联邦, Moscow
L. Kever
Institute of Cytology, the Russian Academy of Sciences
Email: vtetzv@yahoo.com
俄罗斯联邦, St. Petersburg
Ya. Komissarchik
Institute of Cytology, the Russian Academy of Sciences
Email: vtetzv@yahoo.com
俄罗斯联邦, St. Petersburg
V. Tetz
Department of Microbiology and Virology, I. P. Pavlov St. Petersburg First State Medical University, the Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: vtetzv@yahoo.com
俄罗斯联邦, St. Petersburg