Effects of Multicide, Antibacterial Drug, on Staphylococcus Biomembranes


Дәйексөз келтіру

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Аннотация

Drug penetration into bacterial biomembranes is one of the most important factors determining the efficiency of antibacterial therapy. Multicide, antibacterial drug, is a nanomolecule 1.3-2.0 nm in size, easily penetrating into staphylococcus biomembranes and causing rapid death of bacteria. The drug efficiency depends on its concentration and duration of exposure. Bacteria die as a result of cell wall perforation, which is associated with changes in its morphology and release of DNA from bacterial cell into the environment. Our results indicate the efficiency of primary damage to bacterial wall leading to elimination of biomembranes.

Авторлар туралы

G. Tetz

Department of Microbiology and Virology, I. P. Pavlov St. Petersburg First State Medical University, the Ministry of Health of the Russian Federation

Email: vtetzv@yahoo.com
Ресей, St. Petersburg

N. Artemenko

Department of Microbiology and Virology, I. P. Pavlov St. Petersburg First State Medical University, the Ministry of Health of the Russian Federation

Email: vtetzv@yahoo.com
Ресей, St. Petersburg

G. Yankovskii

MISiS National Research Technological Institute

Email: vtetzv@yahoo.com
Ресей, Moscow

L. Kever

Institute of Cytology, the Russian Academy of Sciences

Email: vtetzv@yahoo.com
Ресей, St. Petersburg

Ya. Komissarchik

Institute of Cytology, the Russian Academy of Sciences

Email: vtetzv@yahoo.com
Ресей, St. Petersburg

V. Tetz

Department of Microbiology and Virology, I. P. Pavlov St. Petersburg First State Medical University, the Ministry of Health of the Russian Federation

Хат алмасуға жауапты Автор.
Email: vtetzv@yahoo.com
Ресей, St. Petersburg


© Springer Science+Business Media, LLC, 2017

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