Effect of Electroconvulsive Therapy on Cognitive Functions of Rats with Depression-Like Disorders Induced by Ultrasound Exposure
- 作者: Ushakova V.1, Zubkov E.2, Morozova A.2, Gorlova A.1, Pavlov D.1, Inozemtsev A.1, Chekhonin V.2,3
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隶属关系:
- Department of Higher Nervous Function, M. V. Lomonosov Moscow State University
- Department of Fundamental and Applied Neurobiology, V. P. Serbsky Federal Medical Research Centre for Psychiatry and Narcology, Ministry of Health of the Russian Federation
- N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
- 期: 卷 163, 编号 5 (2017)
- 页面: 599-601
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239115
- DOI: https://doi.org/10.1007/s10517-017-3857-0
- ID: 239115
如何引用文章
详细
We studied the effect of electroconvulsive therapy on cognitive functions in rats with depression-like disorder caused by exposure to ultrasound of varying frequency (20-45 kHz). Object recognition and Morris water-maze tests revealed no negative effects of the therapy on memory. Moreover, positive effect of therapy was demonstrated that manifested in amelioration of memory disturbances in depression-like disorders in these behavioral tests. The results of this study do not support the idea about side effects of electroconvulsive therapy, in particular, development of transient amnesia, and are a prerequisite for a more thorough study of internal mechanisms of the effect of the therapy on cognitive sphere.
作者简介
V. Ushakova
Department of Higher Nervous Function, M. V. Lomonosov Moscow State University
编辑信件的主要联系方式.
Email: scobelevavm@gmail.com
俄罗斯联邦, Moscow
E. Zubkov
Department of Fundamental and Applied Neurobiology, V. P. Serbsky Federal Medical Research Centre for Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: scobelevavm@gmail.com
俄罗斯联邦, Moscow
A. Morozova
Department of Fundamental and Applied Neurobiology, V. P. Serbsky Federal Medical Research Centre for Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: scobelevavm@gmail.com
俄罗斯联邦, Moscow
A. Gorlova
Department of Higher Nervous Function, M. V. Lomonosov Moscow State University
Email: scobelevavm@gmail.com
俄罗斯联邦, Moscow
D. Pavlov
Department of Higher Nervous Function, M. V. Lomonosov Moscow State University
Email: scobelevavm@gmail.com
俄罗斯联邦, Moscow
A. Inozemtsev
Department of Higher Nervous Function, M. V. Lomonosov Moscow State University
Email: scobelevavm@gmail.com
俄罗斯联邦, Moscow
V. Chekhonin
Department of Fundamental and Applied Neurobiology, V. P. Serbsky Federal Medical Research Centre for Psychiatry and Narcology, Ministry of Health of the Russian Federation; N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Email: scobelevavm@gmail.com
俄罗斯联邦, Moscow; Moscow