Effect of Electroconvulsive Therapy on Cognitive Functions of Rats with Depression-Like Disorders Induced by Ultrasound Exposure


Дәйексөз келтіру

Толық мәтін

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Аннотация

We studied the effect of electroconvulsive therapy on cognitive functions in rats with depression-like disorder caused by exposure to ultrasound of varying frequency (20-45 kHz). Object recognition and Morris water-maze tests revealed no negative effects of the therapy on memory. Moreover, positive effect of therapy was demonstrated that manifested in amelioration of memory disturbances in depression-like disorders in these behavioral tests. The results of this study do not support the idea about side effects of electroconvulsive therapy, in particular, development of transient amnesia, and are a prerequisite for a more thorough study of internal mechanisms of the effect of the therapy on cognitive sphere.

Авторлар туралы

V. Ushakova

Department of Higher Nervous Function, M. V. Lomonosov Moscow State University

Хат алмасуға жауапты Автор.
Email: scobelevavm@gmail.com
Ресей, Moscow

E. Zubkov

Department of Fundamental and Applied Neurobiology, V. P. Serbsky Federal Medical Research Centre for Psychiatry and Narcology, Ministry of Health of the Russian Federation

Email: scobelevavm@gmail.com
Ресей, Moscow

A. Morozova

Department of Fundamental and Applied Neurobiology, V. P. Serbsky Federal Medical Research Centre for Psychiatry and Narcology, Ministry of Health of the Russian Federation

Email: scobelevavm@gmail.com
Ресей, Moscow

A. Gorlova

Department of Higher Nervous Function, M. V. Lomonosov Moscow State University

Email: scobelevavm@gmail.com
Ресей, Moscow

D. Pavlov

Department of Higher Nervous Function, M. V. Lomonosov Moscow State University

Email: scobelevavm@gmail.com
Ресей, Moscow

A. Inozemtsev

Department of Higher Nervous Function, M. V. Lomonosov Moscow State University

Email: scobelevavm@gmail.com
Ресей, Moscow

V. Chekhonin

Department of Fundamental and Applied Neurobiology, V. P. Serbsky Federal Medical Research Centre for Psychiatry and Narcology, Ministry of Health of the Russian Federation; N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation

Email: scobelevavm@gmail.com
Ресей, Moscow; Moscow


© Springer Science+Business Media, LLC, 2017

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