Changes in the Structure of the Thymus under Conditions of Various Treatments for Experimental Mammary Tumor
- 作者: Kazakov O.1, Kabakov A.1, Poveshchenko A.1,2, Ishchenko I.1, Poveshchenko O.1,3, Strunkin D.1, Raiter T.1, Michurina S.1, Konenkov V.1
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隶属关系:
- Research Institute of Clinical and Experimental Lymphology
- Novosibirsk State Medical University, Ministry of Health of the Russian Federation
- Novosibirsk State Pedagogical University
- 期: 卷 162, 编号 5 (2017)
- 页面: 654-657
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238433
- DOI: https://doi.org/10.1007/s10517-017-3680-7
- ID: 238433
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详细
Morphological changes in the thymus of female Wistar rats with experimental mammary gland carcinomas were studied. After adjuvant therapy, the area of the cortical matter and density of parenchymal cells in the thymus decreased, while areas of the medulla, connective tissue, and content of immunoblasts and macrophages increased. In the thymuses of rats receiving exogenous DNA, morphological signs of activation of the lymphoid and epithelial components were found: areas of the cortex and medulla, glandular and connective tissue corresponded to the values in intact animals, the counts of lymphocytes in the central part of the cortical matter and of macrophages in all zones of the thymus increased, and lymphocyte migration from the thymus increased (in comparison with the chemotherapy group).
作者简介
O. Kazakov
Research Institute of Clinical and Experimental Lymphology
编辑信件的主要联系方式.
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
A. Kabakov
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology; Novosibirsk State Medical University, Ministry of Health of the Russian Federation
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk
I. Ishchenko
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology; Novosibirsk State Pedagogical University
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk
D. Strunkin
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
T. Raiter
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
S. Michurina
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk
V. Konenkov
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
俄罗斯联邦, Novosibirsk