Changes in the Structure of the Thymus under Conditions of Various Treatments for Experimental Mammary Tumor
- Авторы: Kazakov O.1, Kabakov A.1, Poveshchenko A.1,2, Ishchenko I.1, Poveshchenko O.1,3, Strunkin D.1, Raiter T.1, Michurina S.1, Konenkov V.1
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Учреждения:
- Research Institute of Clinical and Experimental Lymphology
- Novosibirsk State Medical University, Ministry of Health of the Russian Federation
- Novosibirsk State Pedagogical University
- Выпуск: Том 162, № 5 (2017)
- Страницы: 654-657
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238433
- DOI: https://doi.org/10.1007/s10517-017-3680-7
- ID: 238433
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Аннотация
Morphological changes in the thymus of female Wistar rats with experimental mammary gland carcinomas were studied. After adjuvant therapy, the area of the cortical matter and density of parenchymal cells in the thymus decreased, while areas of the medulla, connective tissue, and content of immunoblasts and macrophages increased. In the thymuses of rats receiving exogenous DNA, morphological signs of activation of the lymphoid and epithelial components were found: areas of the cortex and medulla, glandular and connective tissue corresponded to the values in intact animals, the counts of lymphocytes in the central part of the cortical matter and of macrophages in all zones of the thymus increased, and lymphocyte migration from the thymus increased (in comparison with the chemotherapy group).
Об авторах
O. Kazakov
Research Institute of Clinical and Experimental Lymphology
Автор, ответственный за переписку.
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk
A. Kabakov
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology; Novosibirsk State Medical University, Ministry of Health of the Russian Federation
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk; Novosibirsk
I. Ishchenko
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology; Novosibirsk State Pedagogical University
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk; Novosibirsk
D. Strunkin
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk
T. Raiter
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk
S. Michurina
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk
V. Konenkov
Research Institute of Clinical and Experimental Lymphology
Email: kazakoff_oleg@mail.ru
Россия, Novosibirsk
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