Proteomic Study of Blood Serum in Coronary Atherosclerosis

E. M. Stakhneva; I. A. Meshcheryakova; E. A. Demidov; K. V. Starostin; Yu. I. Ragino; S. E. Peltek; M. I. Voevoda

doi:10.1007/s10517-017-3611-7

Proteomic Study of Blood Serum in Coronary Atherosclerosis

作者: Stakhneva E.¹, Meshcheryakova I.², Demidov E.², Starostin K.², Ragino Y.¹, Peltek S.², Voevoda M.¹
隶属关系:
1. Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
2. Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
期: 卷 162, 编号 3 (2017)
页面: 343-345
栏目: Article
URL: https://journals.rcsi.science/0007-4888/article/view/238188
DOI: https://doi.org/10.1007/s10517-017-3611-7
ID: 238188

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Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in protein level were determined. In blood serum of patients with coronary atherosclerosis, the content of C4 complement protein increased and ceruloplasmin level decreased, which is typical of heart failure and coronary heart disease.

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Proteomic Study of Blood Serum in Coronary Atherosclerosis

全文:

详细

作者简介

E. Stakhneva

I. Meshcheryakova

E. Demidov

K. Starostin

Yu. Ragino

S. Peltek

M. Voevoda