Proteomic Study of Blood Serum in Coronary Atherosclerosis
- Autores: Stakhneva E.1, Meshcheryakova I.2, Demidov E.2, Starostin K.2, Ragino Y.1, Peltek S.2, Voevoda M.1
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Afiliações:
- Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Edição: Volume 162, Nº 3 (2017)
- Páginas: 343-345
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238188
- DOI: https://doi.org/10.1007/s10517-017-3611-7
- ID: 238188
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Resumo
Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in protein level were determined. In blood serum of patients with coronary atherosclerosis, the content of C4 complement protein increased and ceruloplasmin level decreased, which is typical of heart failure and coronary heart disease.
Sobre autores
E. Stakhneva
Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Autor responsável pela correspondência
Email: stakhneva@yandex.ru
Rússia, Novosibirsk
I. Meshcheryakova
Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: stakhneva@yandex.ru
Rússia, Novosibirsk
E. Demidov
Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: stakhneva@yandex.ru
Rússia, Novosibirsk
K. Starostin
Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: stakhneva@yandex.ru
Rússia, Novosibirsk
Yu. Ragino
Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: stakhneva@yandex.ru
Rússia, Novosibirsk
S. Peltek
Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: stakhneva@yandex.ru
Rússia, Novosibirsk
M. Voevoda
Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: stakhneva@yandex.ru
Rússia, Novosibirsk