Proteomic Study of Blood Serum in Coronary Atherosclerosis


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Аннотация

Changes in the blood serum proteins were assessed in men with coronary atherosclerosis and without coronary heart disease. Proteins were separated by 2D-electrophoresis, protein fractions were identified by their peptide fingerprint by MALDI method; fractions with more than twofold increase in protein level were determined. In blood serum of patients with coronary atherosclerosis, the content of C4 complement protein increased and ceruloplasmin level decreased, which is typical of heart failure and coronary heart disease.

Об авторах

E. Stakhneva

Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Автор, ответственный за переписку.
Email: stakhneva@yandex.ru
Россия, Novosibirsk

I. Meshcheryakova

Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: stakhneva@yandex.ru
Россия, Novosibirsk

E. Demidov

Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: stakhneva@yandex.ru
Россия, Novosibirsk

K. Starostin

Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: stakhneva@yandex.ru
Россия, Novosibirsk

Yu. Ragino

Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: stakhneva@yandex.ru
Россия, Novosibirsk

S. Peltek

Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: stakhneva@yandex.ru
Россия, Novosibirsk

M. Voevoda

Research Institute of Internal and Preventive Medicine, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: stakhneva@yandex.ru
Россия, Novosibirsk


© Springer Science+Business Media New York, 2017

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