Psychopharmacological Effects of Alkaloid Z77 under Conditions of Posthypoxic Encephalopathy and Mechanisms of Their Development
- 作者: Zyuz’kov G.1,2, Losev E.1, Chaikovskii A.1, Suslov N.1, Zhdanov V.1, Udut E.1, Miroshnichenko L.1, Simanina E.1, Polyakova T.1, Povet’eva T.1, Nesterova Y.1, Stavrova L.1, Udut V.1,2, Minakova M.1, Dygai A.1
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隶属关系:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
- Tomsk National Research State University
- 期: 卷 161, 编号 1 (2016)
- 页面: 45-49
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237078
- DOI: https://doi.org/10.1007/s10517-016-3341-2
- ID: 237078
如何引用文章
详细
Psychopharmacological effects of atisine-type diterpene alkaloid Z77 were studied under conditions of experimental posthypoxic encephalopathy. The preparation had a pronounced cerebroprotective effect consisting in normalization of orientation and exploratory behavior and conditioned activity in experimental animals. These changes were accompanied by significant increase in the number of neural stem cells in the paraventricular region of the brain and markedly enhanced production of neurotrophic growth factors by neural tissue microenvironment cells.
作者简介
G. Zyuz’kov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine; Tomsk National Research State University
编辑信件的主要联系方式.
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk; Tomsk
E. Losev
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
A. Chaikovskii
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
N. Suslov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
V. Zhdanov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
E. Udut
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
L. Miroshnichenko
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
E. Simanina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
T. Polyakova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
T. Povet’eva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
Yu. Nesterova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
L. Stavrova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
V. Udut
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine; Tomsk National Research State University
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk; Tomsk
M. Minakova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
A. Dygai
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: zgn@pharm.tsu.ru
俄罗斯联邦, Tomsk
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