电邮这篇文章 Antitumor Properties of Modified Detonation Nanodiamonds and Sorbed Doxorubicin on the Model of Ehrlich Ascites Carcinoma
- 作者: Medvedeva N.1, Zhukov E.1, Inzhevatkin E.1,2, Bezzabotnov V.1
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隶属关系:
- V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
- Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences
- 期: 卷 160, 编号 3 (2016)
- 页面: 372-375
- 栏目: Nanobiotechnologies
- URL: https://journals.rcsi.science/0007-4888/article/view/236710
- DOI: https://doi.org/10.1007/s10517-016-3174-z
- ID: 236710
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详细
We studied antitumor properties of modified detonation nanodiamonds loaded with doxorubicin on in vivo model of Ehrlich ascites carcinoma. The type of tumor development and morphological characteristics of the liver, kidneys, and spleen were evaluated in experimental animals. Modified nanodiamonds injected intraperitoneally produced no antitumor effect on Ehrlich carcinoma. However, doxorubicin did not lose antitumor activity after sorption on modified nanodiamonds.
作者简介
N. Medvedeva
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
Email: evgen_patolog@mail.ru
俄罗斯联邦, Krasnoyarsk
E. Zhukov
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: evgen_patolog@mail.ru
俄罗斯联邦, Krasnoyarsk
E. Inzhevatkin
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation; Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences
Email: evgen_patolog@mail.ru
俄罗斯联邦, Krasnoyarsk; Krasnoyarsk
V. Bezzabotnov
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
Email: evgen_patolog@mail.ru
俄罗斯联邦, Krasnoyarsk
