Отправить статью по E-mail Antitumor Properties of Modified Detonation Nanodiamonds and Sorbed Doxorubicin on the Model of Ehrlich Ascites Carcinoma
- Авторы: Medvedeva N.1, Zhukov E.1, Inzhevatkin E.1,2, Bezzabotnov V.1
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Учреждения:
- V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
- Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences
- Выпуск: Том 160, № 3 (2016)
- Страницы: 372-375
- Раздел: Nanobiotechnologies
- URL: https://journals.rcsi.science/0007-4888/article/view/236710
- DOI: https://doi.org/10.1007/s10517-016-3174-z
- ID: 236710
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Аннотация
We studied antitumor properties of modified detonation nanodiamonds loaded with doxorubicin on in vivo model of Ehrlich ascites carcinoma. The type of tumor development and morphological characteristics of the liver, kidneys, and spleen were evaluated in experimental animals. Modified nanodiamonds injected intraperitoneally produced no antitumor effect on Ehrlich carcinoma. However, doxorubicin did not lose antitumor activity after sorption on modified nanodiamonds.
Об авторах
N. Medvedeva
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
Email: evgen_patolog@mail.ru
Россия, Krasnoyarsk
E. Zhukov
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: evgen_patolog@mail.ru
Россия, Krasnoyarsk
E. Inzhevatkin
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation; Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences
Email: evgen_patolog@mail.ru
Россия, Krasnoyarsk; Krasnoyarsk
V. Bezzabotnov
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
Email: evgen_patolog@mail.ru
Россия, Krasnoyarsk
