Activity of Cathepsin B and Proteome in the Serum and Brain of Rats with Different Behavioral Activity under Conditions of Metabolic Stress
- Авторы: Kirbaeva N.1, Sharanova N.2, Malinkin A.1, Vasil’ev A.1
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Учреждения:
- Federal Research Center of Nutrition and Biotechnology
- V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
- Выпуск: Том 165, № 6 (2018)
- Страницы: 721-724
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240707
- DOI: https://doi.org/10.1007/s10517-018-4250-3
- ID: 240707
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Аннотация
Study of the brain and serum of male Wistar rats with the metabolic stress model detected changed proteomic profiles of emotiogenic structures and an increase of cathepsin B activity. Antiapoptotic effect of coenzyme Q10, added to the ration, was detected. Differences in the adaptation response of animals with passive and active behavior under conditions of metabolic stress were detected.
Об авторах
N. Kirbaeva
Federal Research Center of Nutrition and Biotechnology
Автор, ответственный за переписку.
Email: n.kirbaeva@gmail.com
Россия, Moscow
N. Sharanova
V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
Email: n.kirbaeva@gmail.com
Россия, Moscow
A. Malinkin
Federal Research Center of Nutrition and Biotechnology
Email: n.kirbaeva@gmail.com
Россия, Moscow
A. Vasil’ev
Federal Research Center of Nutrition and Biotechnology
Email: n.kirbaeva@gmail.com
Россия, Moscow