Activity of Cathepsin B and Proteome in the Serum and Brain of Rats with Different Behavioral Activity under Conditions of Metabolic Stress
- Autores: Kirbaeva N.1, Sharanova N.2, Malinkin A.1, Vasil’ev A.1
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Afiliações:
- Federal Research Center of Nutrition and Biotechnology
- V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
- Edição: Volume 165, Nº 6 (2018)
- Páginas: 721-724
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240707
- DOI: https://doi.org/10.1007/s10517-018-4250-3
- ID: 240707
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Resumo
Study of the brain and serum of male Wistar rats with the metabolic stress model detected changed proteomic profiles of emotiogenic structures and an increase of cathepsin B activity. Antiapoptotic effect of coenzyme Q10, added to the ration, was detected. Differences in the adaptation response of animals with passive and active behavior under conditions of metabolic stress were detected.
Sobre autores
N. Kirbaeva
Federal Research Center of Nutrition and Biotechnology
Autor responsável pela correspondência
Email: n.kirbaeva@gmail.com
Rússia, Moscow
N. Sharanova
V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
Email: n.kirbaeva@gmail.com
Rússia, Moscow
A. Malinkin
Federal Research Center of Nutrition and Biotechnology
Email: n.kirbaeva@gmail.com
Rússia, Moscow
A. Vasil’ev
Federal Research Center of Nutrition and Biotechnology
Email: n.kirbaeva@gmail.com
Rússia, Moscow