Email this article Activity of Cathepsin B and Proteome in the Serum and Brain of Rats with Different Behavioral Activity under Conditions of Metabolic Stress
- Authors: Kirbaeva N.V.1, Sharanova N.E.2, Malinkin A.D.1, Vasil’ev A.V.1
-
Affiliations:
- Federal Research Center of Nutrition and Biotechnology
- V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
- Issue: Vol 165, No 6 (2018)
- Pages: 721-724
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240707
- DOI: https://doi.org/10.1007/s10517-018-4250-3
- ID: 240707
Cite item
Open Access
Access granted
Subscription Access
Abstract
Study of the brain and serum of male Wistar rats with the metabolic stress model detected changed proteomic profiles of emotiogenic structures and an increase of cathepsin B activity. Antiapoptotic effect of coenzyme Q10, added to the ration, was detected. Differences in the adaptation response of animals with passive and active behavior under conditions of metabolic stress were detected.
About the authors
N. V. Kirbaeva
Federal Research Center of Nutrition and Biotechnology
Author for correspondence.
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
N. E. Sharanova
V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
A. D. Malinkin
Federal Research Center of Nutrition and Biotechnology
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
A. V. Vasil’ev
Federal Research Center of Nutrition and Biotechnology
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
