Отправить статью по E-mail Bioavailability of the Phenolic Antioxidant 4-Methyl-2,6-Diisobornylphenol After Oral Administration
- Авторы: Chernysheva G.1, Smolyakova V.1, Yanovskaya E.2, Kutchin A.3, Chukicheva I.3, Udut V.2, Plotnikov M.1
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Учреждения:
- Laboratory of Pharmacology of Blood Circulation
- Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
- Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
- Выпуск: Том 161, № 4 (2016)
- Страницы: 505-507
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237545
- DOI: https://doi.org/10.1007/s10517-016-3448-5
- ID: 237545
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Аннотация
We compared bioavailability of 4-methyl-2,6-diisobornylphenol after single intragastric administration to rats in a dose of 200 mg/kg in starch suspension and in almond oil. Absorption of 4-methyl-2,6-diisobornylphenol in the gastrointestinal tract after administration in almond oil was much more efficient than after administration in aqueous starch mucus.
Об авторах
G. Chernysheva
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Россия, Tomsk
V. Smolyakova
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Россия, Tomsk
E. Yanovskaya
Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Автор, ответственный за переписку.
Email: elena.yanovskaya@pharmso.ru
Россия, Tomsk
A. Kutchin
Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
Email: elena.yanovskaya@pharmso.ru
Россия, Syktyvkar, Komi Republic
I. Chukicheva
Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
Email: elena.yanovskaya@pharmso.ru
Россия, Syktyvkar, Komi Republic
V. Udut
Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: elena.yanovskaya@pharmso.ru
Россия, Tomsk
M. Plotnikov
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Россия, Tomsk
