Enviar artigo por via de e-mail Bioavailability of the Phenolic Antioxidant 4-Methyl-2,6-Diisobornylphenol After Oral Administration
- Autores: Chernysheva G.1, Smolyakova V.1, Yanovskaya E.2, Kutchin A.3, Chukicheva I.3, Udut V.2, Plotnikov M.1
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Afiliações:
- Laboratory of Pharmacology of Blood Circulation
- Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
- Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
- Edição: Volume 161, Nº 4 (2016)
- Páginas: 505-507
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237545
- DOI: https://doi.org/10.1007/s10517-016-3448-5
- ID: 237545
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Resumo
We compared bioavailability of 4-methyl-2,6-diisobornylphenol after single intragastric administration to rats in a dose of 200 mg/kg in starch suspension and in almond oil. Absorption of 4-methyl-2,6-diisobornylphenol in the gastrointestinal tract after administration in almond oil was much more efficient than after administration in aqueous starch mucus.
Sobre autores
G. Chernysheva
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Rússia, Tomsk
V. Smolyakova
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Rússia, Tomsk
E. Yanovskaya
Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Autor responsável pela correspondência
Email: elena.yanovskaya@pharmso.ru
Rússia, Tomsk
A. Kutchin
Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
Email: elena.yanovskaya@pharmso.ru
Rússia, Syktyvkar, Komi Republic
I. Chukicheva
Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
Email: elena.yanovskaya@pharmso.ru
Rússia, Syktyvkar, Komi Republic
V. Udut
Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: elena.yanovskaya@pharmso.ru
Rússia, Tomsk
M. Plotnikov
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Rússia, Tomsk
