Bioavailability of the Phenolic Antioxidant 4-Methyl-2,6-Diisobornylphenol After Oral Administration
- Авторлар: Chernysheva G.1, Smolyakova V.1, Yanovskaya E.2, Kutchin A.3, Chukicheva I.3, Udut V.2, Plotnikov M.1
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Мекемелер:
- Laboratory of Pharmacology of Blood Circulation
- Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
- Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
- Шығарылым: Том 161, № 4 (2016)
- Беттер: 505-507
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237545
- DOI: https://doi.org/10.1007/s10517-016-3448-5
- ID: 237545
Дәйексөз келтіру
Аннотация
We compared bioavailability of 4-methyl-2,6-diisobornylphenol after single intragastric administration to rats in a dose of 200 mg/kg in starch suspension and in almond oil. Absorption of 4-methyl-2,6-diisobornylphenol in the gastrointestinal tract after administration in almond oil was much more efficient than after administration in aqueous starch mucus.
Авторлар туралы
G. Chernysheva
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Ресей, Tomsk
V. Smolyakova
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Ресей, Tomsk
E. Yanovskaya
Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Хат алмасуға жауапты Автор.
Email: elena.yanovskaya@pharmso.ru
Ресей, Tomsk
A. Kutchin
Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
Email: elena.yanovskaya@pharmso.ru
Ресей, Syktyvkar, Komi Republic
I. Chukicheva
Laboratory of Organic Synthesis and Chemistry of Natural Compounds, Institute of Chemistry, Komi Research Center, Ural Division of the Russian Academy of Sciences
Email: elena.yanovskaya@pharmso.ru
Ресей, Syktyvkar, Komi Republic
V. Udut
Laboratory of Physiology, Molecular and Clinical Pharmacology, E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: elena.yanovskaya@pharmso.ru
Ресей, Tomsk
M. Plotnikov
Laboratory of Pharmacology of Blood Circulation
Email: elena.yanovskaya@pharmso.ru
Ресей, Tomsk
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