Cardiomyocyte Autophagia and Morphological Alterations in the Left Ventricular Myocardium during Acute Focal Ischemia
- Авторы: Blagonravov M.1, Korshunova A.1, Azova M.2, Bondar’ S.1, Frolov V.1
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Учреждения:
- Department of General Pathology and Pathological Physiology, Medical Institute of Russian University of People Friendship
- Department of Biology and General Genetics, Medical Institute of Russian University of People Friendship
- Выпуск: Том 160, № 3 (2016)
- Страницы: 398-400
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236716
- DOI: https://doi.org/10.1007/s10517-016-3180-1
- ID: 236716
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Аннотация
In experiments on rabbits we evaluated the intensity of cardiomyocyte autophagia by the level beclin-1 protein and morphology of the left ventricular myocardium on days 1, 3, and 5 after the onset of focal ischemia caused by ligation of the descending branch of the left coronary artery. The morphological alterations in the left ventricular myocardium were accompanied by intensification of cardiomyocyte autophagia, which attained maximum on postligation day 1.
Об авторах
M. Blagonravov
Department of General Pathology and Pathological Physiology, Medical Institute of Russian University of People Friendship
Автор, ответственный за переписку.
Email: blagonravovm@mail.ru
Россия, Moscow
A. Korshunova
Department of General Pathology and Pathological Physiology, Medical Institute of Russian University of People Friendship
Email: blagonravovm@mail.ru
Россия, Moscow
M. Azova
Department of Biology and General Genetics, Medical Institute of Russian University of People Friendship
Email: blagonravovm@mail.ru
Россия, Moscow
S. Bondar’
Department of General Pathology and Pathological Physiology, Medical Institute of Russian University of People Friendship
Email: blagonravovm@mail.ru
Россия, Moscow
V. Frolov
Department of General Pathology and Pathological Physiology, Medical Institute of Russian University of People Friendship
Email: blagonravovm@mail.ru
Россия, Moscow
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