Secretion of Thioredoxin Peroxidase Protein of Cat Liver Fluke Opisthorchis felineus during Modeling of Experimental Opisthorchiasis
- Autores: Petrenko V.1, Pakharukova M.1,2, Kovner A.1, L’vova M.1, Lyakhovich V.2, Mordvinov V.1,2
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Afiliações:
- Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
- Research Institute of Molecular Biology and Biophysics
- Edição: Volume 162, Nº 6 (2017)
- Páginas: 773-776
- Seção: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/238553
- DOI: https://doi.org/10.1007/s10517-017-3710-5
- ID: 238553
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Resumo
Mechanisms of thioredoxin peroxidase secretion by Opisthorchis felineus were studied in vivo and in vitro. Specific antibodies were obtained and used for western blotting and immunohistochemical detection in Syrian hamster model of opisthorchiasis. Secreted thioredoxin peroxidase protein was accumulated in the worm incubation medium under conditions of oxidative stress and in bile duct cells of hamsters with chronic opisthorchiasis.
Sobre autores
V. Petrenko
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Rússia, Novosibirsk
M. Pakharukova
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences; Research Institute of Molecular Biology and Biophysics
Autor responsável pela correspondência
Email: pmaria@yandex.ru
Rússia, Novosibirsk; Novosibirsk
A. Kovner
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Rússia, Novosibirsk
M. L’vova
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences
Email: pmaria@yandex.ru
Rússia, Novosibirsk
V. Lyakhovich
Research Institute of Molecular Biology and Biophysics
Email: pmaria@yandex.ru
Rússia, Novosibirsk
V. Mordvinov
Federal Research Centre Institute of Cytology and Genetics of the Siberian Division of the Russian Academy of Sciences; Research Institute of Molecular Biology and Biophysics
Email: pmaria@yandex.ru
Rússia, Novosibirsk; Novosibirsk
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